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Reference detail
Reference Info.
Pubmed ID 23471001  
RRC ID 27186 
Author Cogoi S, Zorzet S, Rapozzi V, Géci I, Pedersen EB, Xodo LE. 
Title MAZ-binding G4-decoy with locked nucleic acid and twisted intercalating nucleic acid modifications suppresses KRAS in pancreatic cancer cells and delays tumor growth in mice. 
Journal Nucleic Acids Res. 
Published 2013-4 
Volume 41(7) 
Pages 4049-64 
DOI 10.1093/nar/gkt127   
PII gkt127 
MeSH
Animals
Antineoplastic Agents / chemistry
Antineoplastic Agents / pharmacology
Antineoplastic Agents / therapeutic use*
Apoptosis
Binding Sites
Binding, Competitive
Cell Line, Tumor
DNA / chemistry
DNA-Binding Proteins / metabolism*
G-Quadruplexes
Humans
Mice
Mice, SCID
Oligonucleotides / chemistry
Pancreatic Neoplasms / drug therapy*
Pancreatic Neoplasms / genetics
Pancreatic Neoplasms / pathology
Promoter Regions, Genetic
Proto-Oncogene Proteins / antagonists & inhibitors*
Proto-Oncogene Proteins / genetics
Proto-Oncogene Proteins / metabolism
Transcription Factors / metabolism*
Transcriptional Activation
ras Proteins / antagonists & inhibitors*
ras Proteins / genetics
ras Proteins / metabolism
Resource Info.
Species DNA material 
Resource name
pCMV-MAZ (RDB03219); pGEX-hMAZ (RDB05701

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