| RRC ID |
33246
|
| 著者 |
Ishijima J, Uno Y, Nishida C, Matsuda Y.
|
| タイトル |
Genomic structures of the kW1 loci on the Z and W chromosomes in ratite birds: structural changes at an early stage of W chromosome differentiation.
|
| ジャーナル |
Cytogenet Genome Res
|
| Abstract |
The W chromosome of ratite birds shows minimal morphological differentiation and retains homology of genetic linkage and gene order with a substantial stretch of the Z chromosome; however, the molecular structure in the differentiated region is still not well known. The kW1 sequence was isolated from the kiwi as a W-specific DNA marker for PCR-based molecular sexing of ratite birds. In ratite W chromosomes, this sequence commonly contains a ∼200-bp deletion. To characterize the very early event of avian sex chromosome differentiation, we performed molecular cytogenetic analyses of kW1 and its flanking sequences in paleognathous and neognathous birds and reptiles. Female-specific repeats were found in the kW1-flanking sequence of the cassowary (Casuarius casuarius), and the repeats have been amplified in the pericentromeric region of the W chromosomes of ratites, which may have resulted from the cessation of meiotic recombination between the Z and W chromosomes at an early stage of sex chromosome differentiation. The presence of the kW1 sequence in neognathous birds and a crocodilian species suggests that the kW1 sequence was present in the ancestral genome of Archosauria; however, it disappeared in other reptilian taxa and several lineages of neognathous birds.
|
| 巻・号 |
142(4)
|
| ページ |
255-67
|
| 公開日 |
2014-1-1
|
| DOI |
10.1159/000362479
|
| PII |
000362479
|
| PMID |
24820528
|
| MeSH |
Alligators and Crocodiles / genetics
Animals
Base Sequence
Chromosome Mapping
Evolution, Molecular
Female
Male
Molecular Sequence Data
Palaeognathae / genetics*
Sequence Alignment
Sequence Analysis, DNA
Sex Chromosomes / genetics*
Transcription Factors / genetics
|
| IF |
1.114
|
| 引用数 |
1
|
|
WOS 分野
|
GENETICS & HEREDITY
CELL BIOLOGY
|
| リソース情報 |
| ニワトリ・ウズラ |
|
