RRC ID 45236
著者 Tai A, Aburada M, Ito H.
タイトル A simple efficient synthesis and biological evaluation of 3-O-ethylascorbic acid.
ジャーナル Biosci Biotechnol Biochem
Abstract A single-step synthesis of 3-O-ethyl-l-ascorbic acid was performed without the induction of protecting groups. Sodium l-ascorbate reacted with ethyl bromide in DMSO to give 3-O-ethylascorbic acid in a yield of 51.0%. 3-O-Ethylascorbic acid enhanced dibutyryl cyclic AMP-induced neurite outgrowth in PC12 cells.
巻・号 78(12)
ページ 1984-7
公開日 2014-1-1
DOI 10.1080/09168451.2014.946396
PMID 25127395
MeSH Animals Ascorbic Acid / analogs & derivatives* Ascorbic Acid / chemical synthesis Ascorbic Acid / chemistry Ascorbic Acid / pharmacology Bromides / chemistry Bucladesine / metabolism Calcium / metabolism Cell Survival / drug effects Neurites / drug effects* PC12 Cells Rats
IF 1.516
引用数 1
WOS 分野 FOOD SCIENCE & TECHNOLOGY BIOTECHNOLOGY & APPLIED MICROBIOLOGY CHEMISTRY, APPLIED BIOCHEMISTRY & MOLECULAR BIOLOGY
リソース情報
ヒト・動物細胞 PC-12(RCB0009)