論文 - 詳細
RRC ID | 30691 |
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著者 | Tanaka KM, Takahashi A, Fuse N, Takano-Shimizu-Kouno T. |
タイトル | A novel cell death gene acts to repair patterning defects in Drosophila melanogaster. |
ジャーナル | Genetics |
Abstract |
Cell death is a mechanism utilized by organisms to eliminate excess cells during development. Here, we describe a novel regulator of caspase-independent cell death, Mabiki (Mabi), that is involved in the repair of the head patterning defects caused by extra copies of bicoid in Drosophila melanogaster. Mabiki functions together with caspase-dependent cell death mechanisms to provide robustness during development. |
巻・号 | 197(2) |
ページ | 739-42 |
公開日 | 2014-6-1 |
DOI | 10.1534/genetics.114.163337 |
PII | genetics.114.163337 |
PMID | 24671768 |
PMC | PMC4063928 |
MeSH | Animals Body Patterning / genetics* Cell Death / genetics Drosophila Proteins / genetics Drosophila Proteins / metabolism* Drosophila melanogaster / embryology* Drosophila melanogaster / genetics Gene Expression Regulation, Developmental* Gene Knockdown Techniques Head / embryology |
IF | 4.015 |
引用数 | 1 |
WOS 分野 | GENETICS & HEREDITY |
リソース情報 | |
ショウジョウバエ | DrosDel deficiencies |