RRC ID 30691
著者 Tanaka KM, Takahashi A, Fuse N, Takano-Shimizu-Kouno T.
タイトル A novel cell death gene acts to repair patterning defects in Drosophila melanogaster.
ジャーナル Genetics
Abstract Cell death is a mechanism utilized by organisms to eliminate excess cells during development. Here, we describe a novel regulator of caspase-independent cell death, Mabiki (Mabi), that is involved in the repair of the head patterning defects caused by extra copies of bicoid in Drosophila melanogaster. Mabiki functions together with caspase-dependent cell death mechanisms to provide robustness during development.
巻・号 197(2)
ページ 739-42
公開日 2014-6-1
DOI 10.1534/genetics.114.163337
PII genetics.114.163337
PMID 24671768
PMC PMC4063928
MeSH Animals Body Patterning / genetics* Cell Death / genetics Drosophila Proteins / genetics Drosophila Proteins / metabolism* Drosophila melanogaster / embryology* Drosophila melanogaster / genetics Gene Expression Regulation, Developmental* Gene Knockdown Techniques Head / embryology
IF 4.015
引用数 1
WOS 分野 GENETICS & HEREDITY
リソース情報
ショウジョウバエ DrosDel deficiencies