RRC ID 36241
著者 Hales KG, Korey CA, Larracuente AM, Roberts DM.
タイトル Genetics on the Fly: A Primer on the Drosophila Model System.
ジャーナル Genetics
Abstract Fruit flies of the genus Drosophila have been an attractive and effective genetic model organism since Thomas Hunt Morgan and colleagues made seminal discoveries with them a century ago. Work with Drosophila has enabled dramatic advances in cell and developmental biology, neurobiology and behavior, molecular biology, evolutionary and population genetics, and other fields. With more tissue types and observable behaviors than in other short-generation model organisms, and with vast genome data available for many species within the genus, the fly's tractable complexity will continue to enable exciting opportunities to explore mechanisms of complex developmental programs, behaviors, and broader evolutionary questions. This primer describes the organism's natural history, the features of sequenced genomes within the genus, the wide range of available genetic tools and online resources, the types of biological questions Drosophila can help address, and historical milestones.
巻・号 201(3)
ページ 815-42
公開日 2015-11-1
DOI 10.1534/genetics.115.183392
PII 201/3/815
PMID 26564900
PMC PMC4649653
MeSH Animals Drosophila* / genetics Drosophila* / physiology Models, Biological* Models, Genetic
IF 4.015
引用数 61
WOS 分野 GENETICS & HEREDITY
リソース情報
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