| RRC ID |
36122
|
| 著者 |
Akitomo S, Egi Y, Nakamura Y, Suetsugu Y, Oishi K, Sakamoto K.
|
| タイトル |
Genome-wide microarray screening for Bombyx mori genes related to transmitting the determination outcome of whether to produce diapause or nondiapause eggs.
|
| ジャーナル |
Insect Sci
|
| Abstract |
The bivoltine silkworm Bombyx mori (Lepidoptera: Bombycidae) exhibits a maternally controlled embryonic diapause. Maternal silkworms decide whether to lay diapause or nondiapause eggs depending on environmental factors such as the temperature and photoperiod during the egg and larval stages, and then induce diapause eggs during the pupal stage. However, little is known about the molecular mechanism that conveys the outcome of whether to produce diapause or nondiapause eggs from the egg or larval stages to the pupal stage. This study used microarray analysis to investigate differentially expressed genes in the larval brains of diapause- and nondiapause-egg producers, to which bivoltine silkworms were destined by thermal or photic stimulation during the egg stage. The cytochrome P450 18a1 and Krüppel homolog 1 genes were upregulated in producers of diapause eggs compared with those of nondiapause eggs under both experimental conditions. Cytochrome P450 18a1 encodes a key enzyme for steroid hormone inactivation and Krüppel homolog 1 is an early juvenile hormone-inducible gene that mediates the repression of metamorphosis. The upregulation of these genes during the larval stage might be involved in the signaling pathway that transmits information about the diapause program from the egg stage to the pupal stage in the silkworm.
|
| 巻・号 |
24(2)
|
| ページ |
187-193
|
| 公開日 |
2017-4-1
|
| DOI |
10.1111/1744-7917.12297
|
| PMID |
26596800
|
| MeSH |
Animals
Bombyx / genetics*
Bombyx / growth & development
Bombyx / metabolism
Brain / growth & development
Brain / metabolism
Cytochrome P-450 Enzyme System / genetics
Cytochrome P-450 Enzyme System / metabolism
Diapause, Insect / genetics*
Female
Gene Expression Regulation, Developmental
Genome, Insect
Larva / genetics
Larva / growth & development
Larva / metabolism
Oligonucleotide Array Sequence Analysis
Oviposition / genetics
Ovum
Photoperiod
Pupa / genetics
Pupa / growth & development
Pupa / metabolism
Temperature
|
| IF |
2.791
|
| 引用数 |
1
|
|
WOS 分野
|
ENTOMOLOGY
|
| リソース情報 |
| カイコ |
p50 |
