RRC ID 34264
著者 Arakawa H, Takasaki M, Tajima N, Fukamachi H, Igarashi T.
タイトル Antibacterial activities of persimmon extracts relate with their hydrogen peroxide concentration.
ジャーナル Biol Pharm Bull
Abstract Persimmon, a deciduous tree of the family Ebenaceae, is found throughout East Asia and contains high levels of tannins. This class of natural compounds exhibit favorable toxicity profiles along with bactericidal activity without the emergence of resistant bacteria, suggesting potential medical applications. Consistent with these observations, persimmon leaves show antibacterial activity. However, the mechanism of persimmon antibacterial activity remains unknown. In the present work, we demonstrate that the antibacterial activity of persimmon reflects the generation of reactive oxygen from tannins. The identification and quantification of reactive oxygen generated from persimmon and the level of antibacterial activity were determined.
巻・号 37(7)
ページ 1119-23
公開日 2014-1-1
DOI 10.1248/bpb.b13-00952
PII DN/JST.JSTAGE/bpb/b13-00952
PMID 24805207
MeSH Anti-Bacterial Agents / isolation & purification Anti-Bacterial Agents / pharmacology* Bacteria / drug effects Bacteria / growth & development Colony Count, Microbial Diospyros / chemistry* Hydrogen Peroxide / analysis* Microbial Sensitivity Tests Plant Components, Aerial / chemistry Plant Extracts / isolation & purification Plant Extracts / pharmacology*
IF 1.863
引用数 11
WOS 分野 PHARMACOLOGY & PHARMACY
リソース情報
一般微生物 JCM 1134 JCM 1222 JCM 5803 JCM 20026