RRC ID 28742
著者 Fujii T, Ozaki M, Masamoto T, Katsuma S, Abe H, Shimada T.
タイトル A Bombyx mandarina mutant exhibiting translucent larval skin is controlled by the molybdenum cofactor sulfurase gene.
ジャーナル Genes Genet Syst
Abstract During the maintenance of the wild silkworm, Bombyx mandarina, a mutant phenotype exhibiting translucent skin was identified. Based on the crossing experiments with the domesticated silkworm, Bombyx mori, we found that the mutant was controlled by molybdenum cofactor sulfurase (MoCoS) gene. We designated the mutant ''Ozaki's translucent'' (og(Z)). We found a 2.1-kb deletion containing the transcription initiation site, exons 1 and 2, and the 5' end of exon 3 of the MoCoS gene. The transcript of the MoCoS gene was not detected in the og(Z) homozygote. We concluded that og(Z) is a complete loss-of-function allele generated by a disruption of the MoCoS gene.
巻・号 84(2)
ページ 147-52
公開日 2009-4-1
DOI 10.1266/ggs.84.147
PII JST.JSTAGE/ggs/84.147
解説 ogz(尾崎油)の原因遺伝子はMoCo sulfuraseである。MoCo sulfuraseはモリブデン補酵素硫黄化酵素をコードする。 ogz系統では、MoCo sulfuraseのエクソン1~3が欠失している。
PMID 19556708
MeSH Animals Bombyx / enzymology Bombyx / genetics* Bombyx / metabolism Cloning, Molecular Coenzymes / metabolism Crosses, Genetic Female Gene Expression Regulation, Enzymologic Insect Proteins / genetics* Insect Proteins / metabolism Larva / enzymology Larva / genetics Larva / metabolism Male Metalloproteins / metabolism Molecular Sequence Data Molybdenum Cofactors Mutation* Pteridines / metabolism Reverse Transcriptase Polymerase Chain Reaction Sequence Analysis, DNA Sulfurtransferases / genetics* Sulfurtransferases / metabolism
IF 0.917
引用数 5
WOS 分野 GENETICS & HEREDITY BIOCHEMISTRY & MOLECULAR BIOLOGY
リソース情報
カイコ o35