RRC ID 29763
著者 Jochimsen B, Nygaard P, Vestergaard T.
タイトル Location on the chromosome of Escherichia coli of genes governing purine metabolism. Adenosine deaminase (add), guanosine kinase (gsk) and hypoxanthine phosphoribosyltransferase (hpt).
ジャーナル Mol Gen Genet
Abstract Genes coding for enzymes functioning in purine salvage pathways have been located on the chromosome of Escherichia coli. The gene add encoding adenosine deaminase was located by transduction at 31 min, the gene order was established to be man-uidA-add-aroD. A deletion covering man-uidA-add was obtained. The gene gsk encoding guanosine kinase was cotransducible with purE and shown to be located at 13 min. The gene hpt encoding hypoxanthine phosphoribosyltransferase was cotransducible with tonA indicating a location at 3 min. The location of the gene gpt encoding guanine (xanthine) phosphoribosyltransferase in the proA-proB region was confirmed.
巻・号 143(1)
ページ 85-91
公開日 1975-12-30
DOI 10.1007/BF00269424
PMID 765747
MeSH Adenine Phosphoribosyltransferase Adenosine / metabolism Adenosine Deaminase / biosynthesis* Chromosome Deletion Chromosome Mapping Chromosomes, Bacterial* Conjugation, Genetic Escherichia coli / enzymology* Escherichia coli / metabolism Genes* Guanine Guanosine / metabolism Hypoxanthine Phosphoribosyltransferase / biosynthesis* Hypoxanthines / metabolism Inosine / metabolism Mutation Nucleoside Deaminases / biosynthesis* Pentosyltransferases / biosynthesis* Purines / metabolism Recombination, Genetic Transduction, Genetic Transferases Xanthines
リソース情報
原核生物(大腸菌) ME5440 ME5438 ME5439