RRC ID 30087
著者 Whalen WA, Berg CM.
タイトル Gratuitous repression of avtA in Escherichia coli and Salmonella typhimurium.
ジャーナル J Bacteriol
Abstract avtA , which encodes transaminase C (alanine-valine transaminase), is repressed by excess-L-alanine or L-leucine, and also by limitation for any of a number of amino acids in Escherichia coli and Salmonella typhimurium. Amino acid limitation causes repression by promoting the accumulation of L-alanine or L-leucine or both. avtA is also repressed by L-alpha-aminobutyric acid and other nonprotein amino acids which are structurally similar to L-alanine. We hypothesize that L-alanine and L-alpha-aminobutyric acid, whose syntheses are catalyzed by transaminase C, are the true corepressors of avtA . Repression by structural analogs of the true corepressors is termed gratuitous repression.
巻・号 158(2)
ページ 571-4
公開日 1984-5-1
DOI 10.1128/jb.158.2.571-574.1984
PMID 6373721
PMC PMC215466
MeSH Alanine / pharmacology Amino Acids / pharmacology* Aminobutyrates / pharmacology Enzyme Repression / drug effects Escherichia coli / enzymology* Escherichia coli / genetics Genes, Bacterial Leucine / pharmacology Salmonella typhimurium / enzymology* Salmonella typhimurium / genetics Structure-Activity Relationship Transaminases / biosynthesis* Transaminases / genetics
IF 3.006
引用数 15
WOS 分野 MICROBIOLOGY
リソース情報
原核生物(大腸菌) ME8311 ME8273 ME8312 ME8334 ME8335 ME8336 ME8337 ME8339 ME8340 ME8341 ME8342 ME8343 ME8352 ME8355 ME8356 ME8345 ME8360 ME8359 ME8350 ME8344 ME8346 ME8347 ME8349 ME8351 ME8353 ME8354 ME8361 ME8348 ME8748