RRC ID 30168
著者 Kogoma T, von Meyenburg K.
タイトル The origin of replication, oriC, and the dnaA protein are dispensable in stable DNA replication (sdrA) mutants of Escherichia coli K-12.
ジャーナル EMBO J
Abstract The sdrA224 mutants of Escherichia coli K-12, capable of continued DNA replication in the absence of protein synthesis (stable DNA replication), tolerate inactivation of the dnaA gene by insertion of transposon Tn10. Furthermore, oriC, the origin of E. coli chromosome replication, can be deleted from the chromosome of sdrA mutants without loss of viability. The results suggest the presence of a second, normally repressed, initiation system for chromosome replication alternative to the 'normal' dnaA+ oriC+-dependent initiation mechanism.
巻・号 2(3)
ページ 463-8
公開日 1983-1-1
DOI 10.1002/j.1460-2075.1983.tb01445.x
PMID 11894964
PMC PMC555155
MeSH Bacterial Proteins / genetics* DNA Replication* DNA, Bacterial / biosynthesis* DNA-Binding Proteins / genetics* Escherichia coli / genetics* Genes, Viral Mutagenesis Replication Origin* Transposases
IF 9.889
引用数 103
WOS 分野 BIOCHEMISTRY & MOLECULAR BIOLOGY CELL BIOLOGY
リソース情報
原核生物(大腸菌) ME9157 ME9156 ME9158 ME9139 ME9138 ME9131