RRC ID 3307
著者 Eydallin G, Viale AM, Morán-Zorzano MT, Muñoz FJ, Montero M, Baroja-Fernández E, Pozueta-Romero J.
タイトル Genome-wide screening of genes affecting glycogen metabolism in Escherichia coli K-12.
ジャーナル FEBS Lett
Abstract A systematic and comprehensive gene-disrupted mutant collection of E. coli K-12 was used to identify genes whose deletions affect glycogen accumulation. Of the 3985 non-essential gene mutants of the collection, 35 displayed a glycogen-excess phenotype, whereas 30 displayed either glycogen-less or glycogen-deficient phenotypes. The genes whose deletions affect glycogen accumulation were classified into various functional categories, including energy production, envelope composition and integrity, protein translation and stability, transport of inorganic ions and nucleotides, and metabolism of carbohydrates and amino acids. The overall data indicate that glycogen metabolism is highly interconnected with a wide variety of cellular processes in E. coli.
巻・号 581(16)
ページ 2947-53
公開日 2007-6-26
DOI 10.1016/j.febslet.2007.05.044
PII S0014-5793(07)00571-6
PMID 17543954
MeSH Amino Acids / metabolism Bacterial Outer Membrane Proteins / metabolism Carbohydrate Metabolism / genetics Energy Metabolism / genetics Escherichia coli K12 / genetics* Escherichia coli K12 / metabolism* Gene Deletion Genes, Bacterial Genome, Bacterial* Genomics / methods Glycogen / metabolism*
IF 3.057
引用数 41
WOS 分野 BIOPHYSICS BIOCHEMISTRY & MOLECULAR BIOLOGY CELL BIOLOGY
リソース情報
原核生物(大腸菌) ME9062 (BW25113) Keio collection