| RRC ID |
3363
|
| 著者 |
Fujii T, Tanaka N, Yokoyama T, Ninaki O, Oshiki T, Ohnuma A, Tazima Y, Banno Y, Ajimura M, Mita K, Seki M, Ohbayashi F, Shimada T, Abe H.
|
| タイトル |
The female-killing chromosome of the silkworm, Bombyx mori, was generated by translocation between the Z and W chromosomes.
|
| ジャーナル |
Genetica
|
| Abstract |
Bombyx mori is a female-heterogametic organism (female, ZW; male, ZZ) that appears to have a putative feminizing gene (Fem) on the W chromosome. The paternally transmitted mutant W chromosome, Df(p ( Sa ) + ( p )W + ( od ))Fem, derived from the translocation-carrying W chromosome (p ( Sa ) + ( p )W + ( od )), is inert as femaleness determinant. Moreover, this Df(p ( Sa ) + ( p )W + ( od ))Fem chromosome has been thought to have a female-killing factor because no female larvae having the Df(p ( Sa ) + ( p )W + ( od ))Fem chromosome are produced. Initially, to investigate whether the Df(p ( Sa ) + ( p )W + ( od ))Fem chromosome contains any region of the W chromosome or not, we analyzed the presence or absence of 12 W-specific RAPD markers. The Df(p ( Sa ) + ( p )W + ( od ))Fem chromosome contained 3 of 12 W-specific RAPD markers. These results strongly indicate that the Df(p ( Sa ) + ( p )W + ( od ))Fem chromosome contains the region of the W chromosome. Moreover, by using phenotypic and molecular markers, we confirmed that the Df(p ( Sa ) + ( p )W + ( od ))Fem chromosome is connected with a partially deleted Z chromosome and that this fused chromosome behaves as a Z chromosome during male meiosis. Furthermore, we demonstrated that the ZZW-type triploid female having the Df(p ( Sa ) + ( p )W + ( od ))Fem chromosome is viable. Therefore, we concluded that the Df(p ( Sa ) + ( p )W + ( od ))Fem chromosome does not have a female-killing factor but that partial deletion of the Z chromosome causes the death of the ZW-type diploid female having the Df(p ( Sa ) + ( p )W + ( od ))Fem chromosome. Additionally, our results of detailed genetic analyses strongly indicate that the female-killing chromosome composed of the Df(p ( Sa ) + ( p )W + ( od ))Fem chromosome and deleted Z chromosome was generated by translocation between the Z chromosome and the translocation-carrying W chromosome, p ( Sa ) + ( p )W + ( od ).
|
| 巻・号 |
127(1-3)
|
| ページ |
253-65
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| 公開日 |
2006-5-1
|
| DOI |
10.1007/s10709-005-4147-8
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| PMID |
16850229
|
| MeSH |
Animals
Animals, Inbred Strains
Bombyx / embryology
Bombyx / genetics*
Chromosome Breakage
Chromosome Deletion
Eggs
Female
Feminization / genetics
Genes, Lethal*
Genetic Markers
Genotype
Male
Polymorphism, Restriction Fragment Length
Polyploidy
Sex Characteristics
Sex Chromosome Aberrations*
Sex Determination Analysis
Survival Analysis
Translocation, Genetic / physiology*
|
| IF |
1.186
|
| 引用数 |
10
|
|
WOS 分野
|
GENETICS & HEREDITY
|
| リソース情報 |
| カイコ |
p50 |
