| 著者 |
Maeda M, Kuwayama H, Yokoyama M, Nishio K, Morio T, Urushihara H, Katoh M, Tanaka Y, Saito T, Ochiai H, Takemoto K, Yasukawa H, Takeuchi I.
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| Abstract |
We analyzed the spatial expression patterns of the genes involved in myosin function by in situ hybridization at the tipped aggregate and early culmination stages of Dictyostelium. Myosin heavy chain II mRNA was enriched in the anterior prestalk region of the tipped aggregates, whereas it disappeared from there and began to appear in both upper and lower cups of the early culminants. Similarly, mRNAs for essential light chain, regulatory light chain, myosin light chain kinase A, and myosin heavy chain kinase C were enriched in the prestalk region of the tipped aggregates. However, expression of these genes was distinctively regulated in the early culminants. These findings suggest the existence of mechanisms responsible for the expression of particular genes.
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