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Reference Info.
Pubmed ID 23878397  
RRC ID 28098 
Author Tran TA, Kinch L, Peña-Llopis S, Kockel L, Grishin N, Jiang H, Brugarolas J. 
Title Platelet-derived growth factor/vascular endothelial growth factor receptor inactivation by sunitinib results in Tsc1/Tsc2-dependent inhibition of TORC1. 
Journal Mol. Cell. Biol. 
Published 2013-10 
Volume 33(19) 
Pages 3762-79 
DOI 10.1128/MCB.01570-12   
PII MCB.01570-12 
Amino Acid Sequence
Antineoplastic Agents / pharmacology
Blotting, Western
Cell Cycle Proteins / genetics
Cell Cycle Proteins / metabolism*
Cell Line
Cell Proliferation / drug effects
Cells, Cultured
Drosophila Proteins / chemistry
Drosophila Proteins / genetics
Drosophila Proteins / metabolism*
Endothelial Cells / cytology
Endothelial Cells / drug effects
Endothelial Cells / metabolism
Hemocytes / cytology
Hemocytes / drug effects
Hemocytes / metabolism
Indoles / chemistry
Indoles / metabolism
Indoles / pharmacology*
Models, Molecular
Molecular Sequence Data
Multiprotein Complexes / antagonists & inhibitors
Multiprotein Complexes / genetics
Multiprotein Complexes / metabolism*
Protein Structure, Tertiary
Pyrroles / chemistry
Pyrroles / metabolism
Pyrroles / pharmacology*
RNA Interference
Receptor Protein-Tyrosine Kinases / chemistry
Receptor Protein-Tyrosine Kinases / genetics
Receptor Protein-Tyrosine Kinases / metabolism*
Sequence Homology, Amino Acid
TOR Serine-Threonine Kinases / antagonists & inhibitors
TOR Serine-Threonine Kinases / genetics
TOR Serine-Threonine Kinases / metabolism*
Tumor Suppressor Proteins / genetics
Tumor Suppressor Proteins / metabolism
Resource Info.
Species Drosophila 
Resource name

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