| RRC ID |
11555
|
| 著者 |
Nozawa M, Aotsuka T, Tamura K.
|
| タイトル |
A novel chimeric gene, siren, with retroposed promoter sequence in the Drosophila bipectinata complex.
|
| ジャーナル |
Genetics
|
| Abstract |
Retrotransposons often produce a copy of host genes by their reverse transcriptase activity operating on host gene transcripts. Since transcripts normally do not contain promoter, a retroposed gene copy usually becomes a retropseudogene. However, in Drosophila bipectinata and a closely related species we found a new chimeric gene, whose promoter was likely produced by retroposition. This chimeric gene, named siren, consists of a tandem duplicate of Adh and a retroposed fragment of CG11779 containing the promoter and a partial intron in addition to the first exon. We found that this unusual structure of a retroposed fragment was obtained by retroposition of nanos, which overlaps with CG11779 on the complementary strand. The potential of retroposition to produce a copy of promoter and intron sequences in the context of gene overlapping was demonstrated.
|
| 巻・号 |
171(4)
|
| ページ |
1719-27
|
| 公開日 |
2005-12-1
|
| DOI |
10.1534/genetics.105.041699
|
| PII |
genetics.105.041699
|
| PMID |
16143626
|
| PMC |
PMC1456098
|
| MeSH |
Alcohol Dehydrogenase
Alcohol Oxidoreductases / genetics
Amino Acid Sequence
Animals
Base Sequence
Cloning, Molecular
Drosophila / genetics*
Drosophila Proteins / genetics
Evolution, Molecular*
Genetic Linkage
Models, Genetic
Molecular Sequence Data
Mutant Chimeric Proteins / genetics*
Phylogeny
Promoter Regions, Genetic / genetics*
RNA-Binding Proteins / genetics
Retroelements / genetics*
Reverse Transcriptase Polymerase Chain Reaction
Sequence Analysis, DNA
|
| IF |
4.015
|
| 引用数 |
16
|
|
WOS 分野
|
GENETICS & HEREDITY
|
| リソース情報 |
| ショウジョウバエ |
|
