RRC ID |
28742
|
著者 |
Fujii T, Ozaki M, Masamoto T, Katsuma S, Abe H, Shimada T.
|
タイトル |
A Bombyx mandarina mutant exhibiting translucent larval skin is controlled by the molybdenum cofactor sulfurase gene.
|
ジャーナル |
Genes Genet Syst
|
Abstract |
During the maintenance of the wild silkworm, Bombyx mandarina, a mutant phenotype exhibiting translucent skin was identified. Based on the crossing experiments with the domesticated silkworm, Bombyx mori, we found that the mutant was controlled by molybdenum cofactor sulfurase (MoCoS) gene. We designated the mutant ''Ozaki's translucent'' (og(Z)). We found a 2.1-kb deletion containing the transcription initiation site, exons 1 and 2, and the 5' end of exon 3 of the MoCoS gene. The transcript of the MoCoS gene was not detected in the og(Z) homozygote. We concluded that og(Z) is a complete loss-of-function allele generated by a disruption of the MoCoS gene.
|
巻・号 |
84(2)
|
ページ |
147-52
|
公開日 |
2009-4-1
|
DOI |
10.1266/ggs.84.147
|
PII |
JST.JSTAGE/ggs/84.147
|
解説 |
ogz(尾崎油)の原因遺伝子はMoCo sulfuraseである。MoCo sulfuraseはモリブデン補酵素硫黄化酵素をコードする。 ogz系統では、MoCo sulfuraseのエクソン1~3が欠失している。
|
PMID |
19556708
|
MeSH |
Animals
Bombyx / enzymology
Bombyx / genetics*
Bombyx / metabolism
Cloning, Molecular
Coenzymes / metabolism
Crosses, Genetic
Female
Gene Expression Regulation, Enzymologic
Insect Proteins / genetics*
Insect Proteins / metabolism
Larva / enzymology
Larva / genetics
Larva / metabolism
Male
Metalloproteins / metabolism
Molecular Sequence Data
Molybdenum Cofactors
Mutation*
Pteridines / metabolism
Reverse Transcriptase Polymerase Chain Reaction
Sequence Analysis, DNA
Sulfurtransferases / genetics*
Sulfurtransferases / metabolism
|
IF |
0.917
|
引用数 |
5
|
WOS 分野
|
GENETICS & HEREDITY
BIOCHEMISTRY & MOLECULAR BIOLOGY
|
リソース情報 |
カイコ |
o35 |