| RRC ID |
28822
|
| 著者 |
Watanabe MF, Oishi S, Harda K, Matsuura K, Kawai H, Suzuki M.
|
| タイトル |
Toxins contained in Microcystis species of cyanobacteria (blue-green algae).
|
| ジャーナル |
Toxicon
|
| Abstract |
Cyclic peptide toxins were analyzed for three Microcystis species (M. aeruginosa, M. viridis and M. wesenbergii) using an ODS-silica gel cartridge and high performance liquid chromatography with ODS-silica gel. On strain of M. aeruginosa contained a high amount of microcystin (cyanoginosin) YR and a lesser amount of LR. Three toxins, microcystin-RR, -YR and -LR, were detected in two strains of M. aeruginosa and four of M. viridis. The main component of the toxins of these strains was microcystin-RR. M. wesenbergii showed no peak in the area where the three toxins were obtained in other Microcytisis species by HPLC analysis. LD50 values of the purified toxins of YR and LR were similar, while a lower toxicity was estimated for RR. This explains the relatively weak toxicity of M. viridis whose main component is microcystin-RR.
|
| 巻・号 |
26(11)
|
| ページ |
1017-25
|
| 公開日 |
1988-1-1
|
| DOI |
10.1016/0041-0101(88)90200-0
|
| PMID |
3149802
|
| MeSH |
Animals
Bacterial Toxins*
Chromatography, High Pressure Liquid
Cyanobacteria Toxins
Lethal Dose 50
Magnetic Resonance Spectroscopy
Marine Toxins / isolation & purification
Marine Toxins / toxicity*
Mass Spectrometry
Mice
Microcystins
Microcystis / analysis*
|
| IF |
2.201
|
| 引用数 |
112
|
|
WOS 分野
|
TOXICOLOGY
PHARMACOLOGY & PHARMACY
|
| リソース情報 |
| 藻類 |
NIES-103
NIES-112
NIES-1059
NIES-1084
NIES-3349 |
