論文 - 詳細
| RRC ID | 31757 |
|---|---|
| 著者 | Akao M, Kuroda K. |
| タイトル | Antifungal activity of fumaric acid in mice infected with Candida albicans. |
| ジャーナル | Chem Pharm Bull (Tokyo) |
| Abstract |
An examination was made on the effect of fumaric acid on an experimental systemic candidiasis. Male ICR mice were innoculated into the tail veins with 10(6) yeast cells of Candida albicans and treated with daily intraperitoneal injections of fumaric acid at the dose of 40 mg/kg/d. The results indicated that the administration of fumaric acid was effective in prolonging the survival of animals after the fungal challenge and prevented one-fifth of the treated animals from dying of candidiasis. |
| 巻・号 | 39(11) |
| ページ | 3077-8 |
| 公開日 | 1991-11-1 |
| DOI | 10.1248/cpb.39.3077 |
| PMID | 1799950 |
| MeSH | Animals Antifungal Agents / therapeutic use* Candidiasis / drug therapy* Candidiasis / microbiology Fumarates / therapeutic use* Male Mice Mice, Inbred ICR |
| IF | 1.416 |
| 引用数 | 3 |
| WOS 分野 | CHEMISTRY, MULTIDISCIPLINARY CHEMISTRY, MEDICINAL PHARMACOLOGY & PHARMACY |
| リソース情報 | |
| 病原微生物 | IFM 40009 |