論文 - 詳細
RRC ID | 35392 |
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著者 | Yamamoto K, Oshima T, Nonaka G, Ito H, Ishihama A. |
タイトル | Induction of the Escherichia coli cysK gene by genetic and environmental factors. |
ジャーナル | FEMS Microbiol Lett |
Abstract |
Cysteine synthase A encoded by cysK catalyzes the synthesis of cysteine from O-acetylserine. Expression of cysK in Escherichia coli is under the control of CysB, a LysR family transcription factor. Herein we showed that the expression of cysK is regulated by several genetic and environmental factors in addition to CysB: two genetic factors, OmpR and CysE, and lithium. Based on the findings, we constructed the high-level expression system of cysK. |
巻・号 | 323(1) |
ページ | 88-95 |
公開日 | 2011-10-1 |
DOI | 10.1111/j.1574-6968.2011.02364.x |
PMID | 22092684 |
MeSH | Bacterial Proteins / metabolism Cysteine Synthase / biosynthesis* Escherichia coli / enzymology* Escherichia coli / genetics Escherichia coli Proteins / biosynthesis* Escherichia coli Proteins / metabolism Gene Expression Regulation, Bacterial* Gene Expression Regulation, Enzymologic* Lithium / metabolism Serine O-Acetyltransferase / metabolism Trans-Activators / metabolism Transcriptional Activation* |
IF | 1.987 |
引用数 | 9 |
WOS 分野 | MICROBIOLOGY |
リソース情報 | |
原核生物(大腸菌) |