| RRC ID |
46916
|
| 著者 |
Hu Y, Zheng D, Takizawa K, Mikami Y, Dai L, Yazawa K, Fukushima K, Lu C, Xi L.
|
| タイトル |
Systemic nocardiosis caused by Nocardia concava in China.
|
| ジャーナル |
Med Mycol
|
| Abstract |
A 42-year-old man with polychondritis and a 2-year history of using low-dose prednisone and other immunosuppressive drugs was admitted to our hospital due to persistent high fever of 10 days duration. A strain of Nocardia was twice isolated from his blood and subsequently identified to be N. concava. The patient was initially treated with sulphadiazine sodium, vancomycin and imipenema for 7 days but the symptoms persisted. Consequently, the regimen was changed to sulphadiazine sodium, ciprofloxacin and amikacin sulfate based on the antibiotic susceptibility tests of the Nocardia isolate. The fever disappeared and the patient's condition improved after 10 days of this treatment to the extent that he was discharged. However, 7 days later, the patient's condition deteriorated and he died due to multiple organ failure. This is the first report of N. concava causing systemic nocardiosis in China.
|
| 巻・号 |
49(6)
|
| ページ |
662-6
|
| 公開日 |
2011-8-1
|
| DOI |
10.3109/13693786.2011.555849
|
| PMID |
21284569
|
| MeSH |
Adult
Anti-Bacterial Agents / administration & dosage
Bacteremia / complications
Bacteremia / diagnosis*
Bacteremia / drug therapy
Bacteremia / pathology*
Bacterial Typing Techniques
Blood / microbiology
China
DNA Gyrase / genetics
DNA, Bacterial / chemistry
DNA, Bacterial / genetics
Fatal Outcome
Histocytochemistry
Humans
Liver / pathology
Lung / pathology
Male
Microbial Sensitivity Tests
Molecular Sequence Data
Multiple Organ Failure
Nocardia / isolation & purification*
Nocardia Infections / complications
Nocardia Infections / diagnosis*
Nocardia Infections / drug therapy
Nocardia Infections / pathology*
Phylogeny
Radiography, Abdominal
Radiography, Thoracic
Sequence Analysis, DNA
Tomography, X-Ray Computed
|
| IF |
2.822
|
| 引用数 |
10
|
|
WOS 分野
|
VETERINARY SCIENCES
MYCOLOGY
INFECTIOUS DISEASES
|
| リソース情報 |
| 病原微生物 |
IFM 0354
IFM 0576
IFM 10912 |
