RRC ID |
60285
|
著者 |
Sugimura T, Jounai K, Ohshio K, Fujiwara D.
|
タイトル |
Plasmacytoid dendritic cell dysfunction caused by heat stress is improved by administration of Lactococcus lactis strain plasma in mice.
|
ジャーナル |
Biosci Biotechnol Biochem
|
Abstract |
Plasmacytoid dendritic cells (pDCs) are crucial in anti-viral immunity, acting as regulators in both adaptive and innate immunity. In this study, brief heat stress caused a decrease in splenic pDC activity in mice. Administration of Lactococcus lactis strain Plasma (LC-Plasma) significantly suppressed the decrease in pDC activity and IFN-α production. Abbreviations: LC-Plasma: Lactococcus lactis strain Plasma; LAB: lactic acid bacteria; pDC: plasmacytoid dendritic cell; IFN: interferons; mDC: myeloid dendritic cells.
|
巻・号 |
83(11)
|
ページ |
2140-2143
|
公開日 |
2019-11-1
|
DOI |
10.1080/09168451.2019.1642098
|
PMID |
31318317
|
MeSH |
Animals
Dendritic Cells / immunology*
Heat-Shock Response / immunology*
Lactococcus lactis / physiology*
Mice
|
IF |
1.297
|
引用数 |
0
|
リソース情報 |
一般微生物 |
JCM5805 |