RRC ID 64188
著者 Yue TH, Hock AH, Kiang LC, Mooi LY.
タイトル Phenylethanoid glycosides isolated from Paraboea paniculata.
ジャーナル Nat Prod Commun
Abstract Phytochemical studies of the leaves and rhizomes of Paraboea pa niculata (Gesneriaceae) are reported for the first time. Three phenylethanoid glycosides were isolated and characterized as 3,4-dihydroxyphenethyl-(3"-O-beta-D-apiofuranosyl)-beta-D-glucopyranoside, calceoralarioside E, and acteoside. These isolates exhibited weak cytotoxic activity against the K-562 cell line with a 50% of cell killing rate of 40.18 microM, 27.05 microM, and 27.24 microM, respectively. In the DPPH free radical scavenging assay, their IC50 values were determined as 75.89 microM, 25.00 microM, and 26.04 microM, respectively.
巻・号 7(6)
ページ 775-8
公開日 2012-6-1
PMID 22816305
MeSH Cell Line, Tumor Cell Survival / drug effects Glycosides / adverse effects Glycosides / chemistry* Humans Magnoliopsida / chemistry* Molecular Structure Solid Phase Extraction
IF 0.468
リソース情報
ヒト・動物細胞 K-562