| RRC ID |
78558
|
| 著者 |
Kanegae H, de Souza Suguiura IM, Tashiro R, Konno T, Hou DX, Sano A, Eto T, Ueda K, Hossain MA.
|
| タイトル |
Re-Evaluation of the Cross-Reactions of the Antibody against the Causative Agent for Paracoccidioidomycosis Ceti; Paracoccidioides ceti and the Related Fungal Species.
|
| ジャーナル |
Microorganisms
|
| Abstract |
Paracoccidioidomycosis ceti (PCM-C) is a chronic granulomatous keloidal dermatitis in cetaceans that has been reported worldwide and is caused by Paracoccidioides ceti. Serological cross-reactions among highly pathogenic fungal infections and related diseases have been reported. However, the true cross-reaction of antibodies against P. ceti has remained unknown due to the use of positive control sera from infected dolphins. This study aimed to re-evaluate antibodies from mechanically dislodged fungal cells in the infected tissue of a PCM-C case and demonstrate the actual cross-reaction. The results revealed a limited cross-reaction between PCM-C and paracoccidioidomycosis, while the antibodies did not react with other pathogens such as Coccidioides posadasii, Histoplasama capsulatum, and Arthrographis kalrae. Thus, the method for evaluation of the antibody against PCM-C is reliable, and there is potential for epidemiological study.
|
| 巻・号 |
11(10)
|
| 公開日 |
2023-9-28
|
| DOI |
10.3390/microorganisms11102428
|
| PII |
microorganisms11102428
|
| PMID |
37894086
|
| PMC |
PMC10609003
|
| リソース情報 |
| 病原真核微生物 |
Ajellomyces capsulatus IFM 41329, Arthrographis kalrae IFM 55165 |
