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  • Search Condition : Filter (MeSH = Amyotrophic Lateral Sclerosis* / genetics)
Species Resource Title
Zebrafish hspGFFDMC130A, UAS:GFP, UAS:GCaMP7a, SAIGFF213A Dysregulated TDP-43 proteostasis perturbs excitability of spinal motor neurons during brainstem-mediated fictive locomotion in zebrafish.
Human and Animal Cells YST-1(RCB2136) Schwann cell derived-peroxiredoxin protects motor neurons against hydrogen peroxide-induced cell death in mouse motor neuron cell line NSC-34.
Human and Animal Cells , DNA material 201B7(HPS0063) , CSII-EF-MCS-IRES2-Venus (RDB04384) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) Monomerization of TDP-43 is a key determinant for inducing TDP-43 pathology in amyotrophic lateral sclerosis.
Medaka OK-Cab (MT830) Optineurin deficiency impairs autophagy to cause interferon beta overproduction and increased survival of mice following viral infection
C.elegans tm1287 Targeting the NEDP1 enzyme to ameliorate ALS phenotypes through stress granule disassembly.
Zebrafish SAGFF(LF)73 , SAIGFF213A , UAS:mRFP1-TDP-43z , UAS:mRFP1-CRY2olig , UAS:EGFP , mnr2b-hs:Gal4 Optogenetic interrogation of TDP-43 cytotoxicity in a zebrafish ALS model
Drosophila Loss of amyotrophic lateral sclerosis risk factor SCFD1 causes motor dysfunction in Drosophila.