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  • Search Condition : Filter (MeSH = Antimetabolites, Antineoplastic / pharmacology*)
Species Resource Title
Human and Animal Cells MKN45(RCB1001) , MKN1(RCB1003) , HeLa(RCB0007) Carcinoembryonic antigen-specific suicide gene therapy of cytosine deaminase/5-fluorocytosine enhanced by the cre/loxP system in the orthotopic gastric carcinoma model.
Human and Animal Cells Kato III(RCB2088) , MKN74(RCB1002) , NUGC-4(RCB1939) , GSS(RCB2277) , GCIY(RCB0555) , MKN45(RCB1001) A compensatory role of NF-κB to p53 in response to 5-FU-based chemotherapy for gastric cancer cell lines.
DNA material PINK1_WT-IRES-GFP-NLS (RDB18946) , PINK1_KD-IRES-GFP-NLS (RDB18947) , MUL1_WT-IRES-GFP-NLS (RDB18948) , MUL1_LD-IRES-GFP-NLS (RDB18949) Gemcitabine induces Parkin-independent mitophagy through mitochondrial-resident E3 ligase MUL1-mediated stabilization of PINK1.
Human and Animal Cells MKN45(RCB1001) , MKN74(RCB1002) Inhibition of PI3K suppresses propagation of drug-tolerant cancer cell subpopulations enriched by 5-fluorouracil.
Human and Animal Cells MIA Paca2(RCB2094) Ribonucleotide reductase is an effective target to overcome gemcitabine resistance in gemcitabine-resistant pancreatic cancer cells with dual resistant factors.
Human and Animal Cells HHUA(RCB0658) Establishment and characterization of monoclonal 5-fluorouracil-resistant cell lines derived from human endometrial adenocarcinoma.
Human and Animal Cells HKBML(RCB0820) GSEA-assisted gene signatures valid for combinations of prognostic markers in PCNSL.
Human and Animal Cells A549(RCB0098) Rho-Associated Protein Kinase (ROCK) Inhibitors Inhibit Survivin Expression and Sensitize Pancreatic Cancer Stem Cells to Gemcitabine.
Human and Animal Cells HKBML(RCB0820) , RAJI(RCB1647) Differential expression of N-linked oligosaccharides in methotrexate-resistant primary central nervous system lymphoma cells.
Human and Animal Cells Hep G2 Concomitant febuxostat enhances methotrexate-induced hepatotoxicity by inhibiting breast cancer resistance protein.
Human and Animal Cells FELV3281-AD(RCB2610) DNA methylation inhibitor causes cell growth retardation and gene expression changes in feline lymphoma cells.
Human and Animal Cells PC-9(RCB4455) Knockdown of POLA2 increases gemcitabine resistance in lung cancer cells.
Prokaryotes E. coli The dominant role of proofreading exonuclease activity of replicative polymerase ε in cellular tolerance to cytarabine (Ara-C).
Human and Animal Cells KLM-1(RCB2138) , T24 NKG2D-directed cytokine-activated killer lymphocyte therapy combined with gemcitabine for patients with chemoresistant metastatic solid tumors.
Human and Animal Cells HeLa MicroRNA-433 negatively regulates the expression of thymidylate synthase (TYMS) responsible for 5-fluorouracil sensitivity in HeLa cells.
Human and Animal Cells NUGC-4(RCB1939) , MKN7(RCB0999) , Kato III(RCB2088) , MKN45(RCB1001) , MKN1(RCB1003) , MKN74(RCB1002) Inhibition of the mTOR/S6K signal is necessary to enhance fluorouracil-induced apoptosis in gastric cancer cells with HER2 amplification.
Human and Animal Cells RERFLC-AI(RCB0444) , A549(RCB0098) , BALB/3T3 clone A31(RCB0005) Antiproliferative action of metformin in human lung cancer cell lines.
Human and Animal Cells HHUA(RCB0658) Impaired death-associated protein kinase-mediated survival signals in 5-fluorouracil-resistant human endometrial adenocarcinoma cells.
Human and Animal Cells SSP-25(RCB1293) , RBE(RCB1292) , TKKK(RCB1907) , TGBC2TKBRCB1130) , TGBC14TKB(RCB1186) , TGBC24TKB(RCB1196) , 293(RCB1637) Genetic alteration of Keap1 confers constitutive Nrf2 activation and resistance to chemotherapy in gallbladder cancer.
Human and Animal Cells Effects of combined administration of DPD-inhibitory oral fluoropyrimidine, S-1, plus paclitaxel on gene expressions of fluoropyrimidine metabolism-related enzymes in human gastric xenografts.