• 87 Hits
  • 検索条件 : 絞込み (MeSH = DNA Breaks, Double-Stranded)
生物種 リソース名 タイトル
ヒト・動物細胞 HUDEP-2(RCB4557) Generation of scalable cancer models by combining AAV-intron-trap, CRISPR/Cas9, and inducible Cre-recombinase.
線虫 tm1524 , tm2026 , tm1086 PARG and BRCA1-BARD1 cooperative function regulates DNA repair pathway choice during gametogenesis.
線虫 rad-54 Aging and sperm signals alter DNA break formation and repair in the C. elegans germline.
線虫 tm5034 Chromatin landscape, DSB levels, and cKU-70/80 contribute to patterning of meiotic DSB processing along chromosomes in C. elegans.
線虫 Continuous double-strand break induction and their differential processing sustain chiasma formation during Caenorhabditis elegans meiosis.
線虫 tm5034 , tm853 , tm1598 , tm3655 Phosphoregulation of DSB-1 mediates control of meiotic double-strand break activity.
線虫 tm1524 , tm3298 Caenorhabditis elegans RMI2 functional homolog-2 (RMIF-2) and RMI1 (RMH-1) have both overlapping and distinct meiotic functions within the BTR complex.
ヒト・動物細胞 HeLa.S3(RCB1525) Optimal timing of a γH2AX analysis to predict cellular lethal damage in cultured tumor cell lines after exposure to diagnostic and therapeutic radiation doses.
遺伝子材料 pET19b-HFS2BP-Full (RDB19176) , pET28C-4930432K21Rik-N (RDB19177) Meiosis-Specific C19orf57/4930432K21Rik/BRME1 Modulates Localization of RAD51 and DMC1 to DSBs in Mouse Meiotic Recombination.
ヒト・動物細胞 THP-1(RCB1189) , 293(RCB1637) , 293T(RCB2202) DNA damage enhances integration of HIV-1 into macrophages by overcoming integrase inhibition.
ヒト・動物細胞 WI-38(RCB0702) , HeLa ATM and SIRT6/SNF2H Mediate Transient H2AX Stabilization When DSBs Form by Blocking HUWE1 to Allow Efficient γH2AX Foci Formation.
ヒト・動物細胞 293T(RCB2202) Structural alteration of DNA induced by viral protein R of HIV-1 triggers the DNA damage response.
ヒト・動物細胞 CHP-134(RCB0487) Co-Inhibition of the DNA Damage Response and CHK1 Enhances Apoptosis of Neuroblastoma Cells.
ヒト・動物細胞 HeLa , HCT116 Cloning, localization and focus formation at DNA damage sites of canine Ku70.
ヒト・動物細胞 HCT116(RCB2979) , MCF7(RCB1904) Human RECQL4 represses the RAD52-mediated single-strand annealing pathway after ionizing radiation or cisplatin treatment.
線虫 tm2026 , tm1524 , tm202 RPA complexes in Caenorhabditis elegans meiosis; unique roles in replication, meiotic recombination and apoptosis.
線虫 tm1857 Surveillance of cohesin-supported chromosome structure controls meiotic progression.
ヒト・動物細胞 GCIY(RCB0555) , OVK18(RCB1903) WRN helicase is a synthetic lethal target in microsatellite unstable cancers.
ヒト・動物細胞 CHO-K1 Effect of mild temperature shift on poly(ADP-ribose) and γH2AX levels in cultured cells.
ヒト・動物細胞 HCT116(RCB2979) Dual pharmacological inhibition of glutathione and thioredoxin systems synergizes to kill colorectal carcinoma stem cells.