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  • Search Condition : Filter (MeSH = DNA Topoisomerases, Type I / genetics*)
Species Resource Title
Human and Animal Cells HCT116(RCB2979) Predominant cellular mitochondrial dysfunction in the TOP3A gene-caused Bloom syndrome-like disorder.
Prokaryotes E. coli Constitutive stable DNA replication in Escherichia coli cells lacking type 1A topoisomerase activity.
Prokaryotes E. coli ME8780 DNA supercoiling in Escherichia coli: topA mutations can be suppressed by DNA amplifications involving the tolC locus.