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  • 8 Hits
  • Search Condition : Filter (MeSH = Fetal Hemoglobin / genetics)
Species Resource Title
Human and Animal Cells HUDEP-2(RCB4557) Editing a γ-globin repressor binding site restores fetal hemoglobin synthesis and corrects the sickle cell disease phenotype.
Human and Animal Cells HUDEP-2(RCB4557) Targeting fetal hemoglobin expression to treat β hemoglobinopathies.
Human and Animal Cells HUDEP-2(RCB4557) Combination of lentiviral and genome editing technologies for the treatment of sickle cell disease.
Human and Animal Cells HUDEP-2(RCB4557) , HUDEP-1(RCB4556) ATF4 Regulates MYB to Increase γ-Globin in Response to Loss of β-Globin.
Human and Animal Cells HUDEP-2(RCB4557) A unified model of human hemoglobin switching through single-cell genome editing.
Human and Animal Cells HUDEP-2(RCB4557) Disrupting the adult globin promoter alleviates promoter competition and reactivates fetal globin gene expression.
Human and Animal Cells HUDEP-2(RCB4557) Base-editing-mediated dissection of a γ-globin cis-regulatory element for the therapeutic reactivation of fetal hemoglobin expression.
Human and Animal Cells HUDEP-2(RCB4557) Activation of γ-globin expression by hypoxia-inducible factor 1α.