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  • 検索条件 : 絞込み (MeSH = Gene Knock-In Techniques)
生物種 リソース名 タイトル
遺伝子材料 pROSA26CAG-GFP-tdsRed (RDB19441) Novel ROSA26 Cre-reporter knock-in C57BL/6N mice exhibiting green emission before and red emission after Cre-mediated recombination.
ヒト・動物細胞 NIH3T3-3-4(RCB1862) In vivo role of phosphorylation of cryptochrome 2 in the mouse circadian clock.
遺伝子材料 pCALNL5 (RDB01862) Endothelial expression of human amyloid precursor protein leads to amyloid β in the blood and induces cerebral amyloid angiopathy in knock-in mice.
ゼブラフィッシュ Tol-056 Loss of PIGK function causes severe infantile encephalopathy and extensive neuronal apoptosis.
メダカ TG1421 Tg(cdh2-eGFP) , TG1422 Tg(eGFP-cbx1b) , TG1423 Tg(eGFP-rab11a) , TG1424 Tg(mapre1b-Linker-3xFlag-mScarlet) , TG1425 Tg(mNeonGreen-HAtag-Linker-myosinh) , TG1426 Tg(mScarlet-pcna) Endogenous protein tagging in medaka using a simplified CRISPR/Cas9 knock-in approach.
ゼブラフィッシュ Tg(nefma:Gal4) Central Vestibular Tuning Arises from Patterned Convergence of Otolith Afferents.
ヒト・動物細胞 ST2(RCB0224) BMP3 suppresses osteoblast differentiation of bone marrow stromal cells via interaction with Acvr2b.
遺伝子材料 T7-NLS hCas9-pA (RDB13130) , pT7-hCas9-mC-polyA (RDB14423) , T7-3xFLAG-NLS-hCAS9-NLS-pA (RDB14602) , T7-3xFLAG-NLS-hCAS9-Cdt1-NLS-pA (RDB14604) , px330-mC (RDB14406) , pX330-Tyr-L (RDB14410) , pX330-Tyr-R (RDB14411) , pX330-mC-Tyr-L (RDB14412) , pX330-mC-Tyr-R (RDB14413) , pX330-Dmd-L (RDB16004) , ... Efficient production of large deletion and gene fragment knock-in mice mediated by genome editing with Cas9-mouse Cdt1 in mouse zygotes.
遺伝子材料 Genome Network Project Human cDNA IRAK049F12 (HGX019732) TBX5 R264K acts as a modifier to develop dilated cardiomyopathy in mice independently of T-box pathway.
ヒト・動物細胞 454E2(HPS0077) Spatiotemporal imaging documented the maturation of the cardiomyocytes from human induced pluripotent stem cells.
ヒト・動物細胞 HUDEP-2(RCB4557) Acute depletion of CTCF directly affects MYC regulation through loss of enhancer-promoter looping.
線虫 tm776 Single copy/knock-in models of ALS SOD1 in C. elegans suggest loss and gain of function have different contributions to cholinergic and glutamatergic neurodegeneration.
ショウジョウバエ 5183R-1 , 5183R-2 , 4322R-1 , 4780R-3 , 4780R-1 , 9668R-2 , 31640R-3 , 7000R-2 , 9668R-1 , 7227R-1 , ... An in vivo RNAi screen uncovers the role of AdoR signaling and adenosine deaminase in controlling intestinal stem cell activity.
ヒト・動物細胞 293T(RCB2202) Sequence-specific retrotransposition of 28S rDNA-specific LINE R2Ol in human cells.
藻類 NIES-48 Highly efficient transgene-free targeted mutagenesis and single-stranded oligodeoxynucleotide-mediated precise knock-in in the industrial microalga Euglena gracilis using Cas9 ribonucleoproteins.
ヒト・動物細胞 Ba/F3(RCB0805) Development of a new knock-in mouse model and evaluation of pharmacological activities of lusutrombopag, a novel, nonpeptidyl small-molecule agonist of the human thrombopoietin receptor c-Mpl.
ヒト・動物細胞 GS-DG1(AES0002) , Mvh-Venus GS(AES0196) Generating Genetically Engineered Mice Using a Spermatogonial Stem Cell-Mediated Method.
線虫 tm3464 Genetic Suppression of Basement Membrane Defects in Caenorhabditis elegans by Gain of Function in Extracellular Matrix and Cell-Matrix Attachment Genes.
ヒト・動物細胞 CHO-K1(RCB0285) Biased genome editing using the local accumulation of DSB repair molecules system.
実験動物マウス , ヒト・動物細胞 RBRC01834 , TT2(AES0014) Zfat expression in ZsGreen reporter gene knock‑in mice: Implications for a novel function of Zfat in definitive erythropoiesis.