• 34 Hits
  • 検索条件 : 絞込み (MeSH = High-Throughput Screening Assays)
生物種 リソース名 タイトル
シロイヌナズナ / 植物培養細胞・遺伝子 rpc00031 Multifunctional chemical inhibitors of the florigen activation complex discovered by structure-based high-throughput screening.
遺伝子材料 pEU-E01-NLRP3-FL-Bls (RDB19445) , pEU-E01-FLAG-ASC-PYD (RDB19446) , pEU-E01-FLAG-ASC-CARD (RDB19447) KN3014, a piperidine-containing small compound, inhibits auto-secretion of IL-1β from PBMCs in a patient with Muckle-Wells syndrome.
ヒト・動物細胞 201B7(HPS0063) Integrated fibroblast growth factor signal disruptions in human iPS cells for prediction of teratogenic toxicity of chemicals.
ゼブラフィッシュ mi340 Identification of drug modifiers for RYR1-related myopathy using a multi-species discovery pipeline.
ヒト・動物細胞 PC-9(RCB4455) Inhibition of heat shock protein 90 destabilizes receptor tyrosine kinase ROR1 in lung adenocarcinoma.
ヒト・動物細胞 MKN45(RCB1001) CRISPR Screens Provide a Comprehensive Assessment of Cancer Vulnerabilities but Generate False-Positive Hits for Highly Amplified Genomic Regions.
ヒト・動物細胞 HeLa(RCB0007) A simple method for producing multiple copies of controlled release small molecule microarrays for cell-based screening.
ヒト・動物細胞 HuCCT1(RCB1960) Discovery of a chemical compound that suppresses expression of BEX2, a dormant cancer stem cell-related protein.
ヒト・動物細胞 HeLa(RCB0007) Screening, Synthesis, and Evaluation of Novel Isoflavone Derivatives as Inhibitors of Human Golgi β-Galactosidase.
ヒト・動物細胞 Ba/F3(RCB0805) Discovery and structure-activity relationships study of positive allosteric modulators of the M3 muscarinic acetylcholine receptor.
一般微生物 JCM 6425 , JCM 6495 , JCM18916 , JCM18922 , JCM18924 , JCM18907 , JCM18908 , JCM18910 Classification of Cutibacterium acnes at phylotype level by MALDI-MS proteotyping.
ヒト・動物細胞 HeLa(RCB0007) , Jurkat(RCB3052) , COLO-320(RCB1193) High throughput development of TCR-mimic antibody that targets survivin-2B80-88/HLA-A*A24 and its application in a bispecific T-cell engager.
一般微生物 JCM 8837 , JCM 9995 , JCM 22676 , JCM 8095 , JCM 14423 , JCM 5089 , JCM 2923 , JCM 2007 5-Methylmellein is a novel inhibitor of fungal sirtuin and modulates fungal secondary metabolite production.
ヒト・動物細胞 G-415(RCB2640) , TGBC1TKB(RCB1129) , TGBC2TKB(RCB1130) , TGBC24TKB(RCB1196) Small molecule inhibitor screening identifified HSP90 inhibitor 17-AAG as potential therapeutic agent for gallbladder cancer.
ヒト・動物細胞 CW-2(RCB0778) Overcoming resistance to HER2 inhibitors through state-specific kinase binding.
シロイヌナズナ / 植物培養細胞・遺伝子 rpc00041 Combination of Synthetic Chemistry and Live-Cell Imaging Identified a Rapid Cell Division Inhibitor in Tobacco and Arabidopsis thaliana.
一般微生物 JCM 7674 , JCM 2529 An Improved Multiplex Real-Time SYBR Green PCR Assay for Analysis of 24 Target Genes from 16 Bacterial Species in Fecal DNA Samples from Patients with Foodborne Illnesses.
酵母 FY18379 Establishment of expression-state boundaries by Rif1 and Taz1 in fission yeast.
遺伝子材料 pDUAL2-HFF1c (RDB06154) , S. pombe ORFeome Entry clone SpENT30G03 (SPW012147) , SpENT23C11 (SPW009259) , SpENT40E03 (SPW016099). Establishment of expression-state boundaries by Rif1 and Taz1 in fission yeast.
線虫 tm3118 The H3K27 demethylase UTX-1 regulates C. elegans lifespan in a germline-independent, insulin-dependent manner.