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論文 - 一覧

  • 12 Hits
  • 検索条件 : 絞込み (MeSH = Janus Kinase 2 / genetics)
生物種 リソース名 タイトル
ヒト・動物細胞 10T1/2(RCB0247) Establishment of isogenic induced pluripotent stem cells with or without pathogenic mutation for understanding the pathogenesis of myeloproliferative neoplasms.
ヒト・動物細胞 Ba/F3-CL1(RCB4474) Identification of putative noncanonical driver mutations in patients with essential thrombocythemia.
ヒト・動物細胞 HUDEP-2(RCB4557) Genome editing to model and reverse a prevalent mutation associated with myeloproliferative neoplasms.
ヒト・動物細胞 StromaNKtert(RCB2350) Bone marrow stroma-secreted cytokines protect JAK2(V617F)-mutated cells from the effects of a JAK2 inhibitor.
ヒト・動物細胞 Ba/F3(RCB0805) RAS-protein activation but not mutation status is an outcome predictor and unifying therapeutic target for high-risk acute lymphoblastic leukemia.
ヒト・動物細胞 MIA Paca2(RCB2094) The JAK/STAT pathway is involved in the upregulation of PD-L1 expression in pancreatic cancer cell lines.
ヒト・動物細胞 MKN45(RCB1001) Crosstalk between bone marrow-derived myofibroblasts and gastric cancer cells regulates cancer stemness and promotes tumorigenesis.
病原微生物 Miliary tuberculosis associated with chronic neutrophilic leukemia.
ヒト・動物細胞 F-36P(RCB0775) Cbl negatively regulates erythropoietin-induced growth and survival signaling through the proteasomal degradation of Src kinase.
ヒト・動物細胞 K562 Inhibition of the PI3K/Akt/GSK3 pathway downstream of BCR/ABL, Jak2-V617F, or FLT3-ITD downregulates DNA damage-induced Chk1 activation as well as G2/M arrest and prominently enhances induction of apoptosis.
ヒト・動物細胞 Hep G2 Crosstalk of humoral and cell-cell contact-mediated signals in postnatal body growth.
遺伝子材料 pRx nZ ires Neo (RDB01699). Proliferation and survival signaling from both Jak2-V617F and Lyn involving GSK3 and mTOR/p70S6K/4EBP1 in PVTL-1 cell line newly established from acute myeloid leukemia transformed from polycythemia vera.