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  • 検索条件 : 絞込み (MeSH = Loss of Function Mutation)
生物種 リソース名 タイトル
線虫 tm6722 , tm6526 Effector and regulator: Diverse functions of C. elegans C-type lectin-like domain proteins.
ショウジョウバエ DGRC#111477 Drosophila septin interacting protein 1 regulates neurogenesis in the early developing larval brain.
シロイヌナズナ / 植物培養細胞・遺伝子 psi00016 Gibberellin Signaling Promotes the Secondary Growth of Storage Roots in Panax ginseng.
メダカ TG1403 olvas-DsRedExpress Generation of biallelic F0 mutants in medaka using the CRISPR/Cas9 system.
線虫 tm1880 Orcokinin neuropeptides regulate sleep in Caenorhabditis elegans.
線虫 tm1036 The Snail transcription factor CES-1 regulates glutamatergic behavior in C. elegans.
ショウジョウバエ 4349R-3 , 4963R-2 Elevating bioavailable iron levels in mitochondria suppresses the defective phenotypes caused by PINK1 loss-of-function in Drosophila melanogaster.
ショウジョウバエ CAS-0004 The Classic Lobe Eye Phenotype of Drosophila Is Caused by Transposon Insertion-Induced Misexpression of a Zinc-Finger Transcription Factor.
線虫 tm3395 , tm4263 Akirin Is Required for Muscle Function and Acts Through the TGF-β Sma/Mab Signaling Pathway in Caenorhabditis elegans Development.
線虫 tm776 Single copy/knock-in models of ALS SOD1 in C. elegans suggest loss and gain of function have different contributions to cholinergic and glutamatergic neurodegeneration.
ヒト・動物細胞 HeLa(RCB0007) ZIP kinase phosphorylated and activated by Rho kinase/ROCK contributes to cytokinesis in mammalian cultured cells.
ショウジョウバエ 31783R-1 , 31783R-2 Jouvence a small nucleolar RNA required in the gut extends lifespan in Drosophila.
ショウジョウバエ The fruit fly at the interface of diagnosis and pathogenic mechanisms of rare and common human diseases.
ミヤコグサ・ダイズ ミヤコグサDNA Loss-of-function of ASPARTIC PEPTIDASE NODULE-INDUCED 1 (APN1) in Lotus japonicus restricts efficient nitrogen-fixing symbiosis with specific Mesorhizobium loti strains.
線虫 tm6691 , tm4374 , tm2862 , tm2572 UNG-1 and APN-1 are the major enzymes to efficiently repair 5-hydroxymethyluracil DNA lesions in C. elegans.
ヒト・動物細胞 PC-9(RCB4455) Functional Genomics Reveals Synthetic Lethality between Phosphogluconate Dehydrogenase and Oxidative Phosphorylation.
ショウジョウバエ 5115R-2 Drosophila jumu modulates apoptosis via a JNK-dependent pathway and is required for other processes in wing development.
線虫 tm3464 Genetic Suppression of Basement Membrane Defects in Caenorhabditis elegans by Gain of Function in Extracellular Matrix and Cell-Matrix Attachment Genes.
ショウジョウバエ DGRC#118829 , DGRC#118830 Genetic Analyses of Elys Mutations in Drosophila Show Maternal-Effect Lethality and Interactions with Nucleoporin Genes.
ヒト・動物細胞 HuH-28(RCB1943) PARP inhibitor olaparib sensitizes cholangiocarcinoma cells to radiation.