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  • Search Condition : Filter (MeSH = Motor Neurons / pathology*)
Species Resource Title
Zebrafish Tg[UAS:mRFP1-TDP-43z] , Tg[UAS:mRFP1-CRY2olig] , Tg[UAS:opTDP-43z] , Tg[mnr2b-hs:EGFP-TDP-43z] , Tg[mnr2b-hs:opTDP-43h] , Tg[mnr2b-hs:opTDP-43hA315T] Optogenetic modulation of TDP-43 oligomerization accelerates ALS-related pathologies in the spinal motor neurons.
C.elegans tm776 Single copy/knock-in models of ALS SOD1 in C. elegans suggest loss and gain of function have different contributions to cholinergic and glutamatergic neurodegeneration.
Drosophila Neuron-specific knockdown of Drosophila PDHB induces reduction of lifespan, deficient locomotive ability, abnormal morphology of motor neuron terminals and photoreceptor axon targeting.
Zebrafish Tg(CM-isl1:GFP) Variants in EXOSC9 Disrupt the RNA Exosome and Result in Cerebellar Atrophy with Spinal Motor Neuronopathy.
C.elegans tm1689 Rescue of ATXN3 neuronal toxicity in Caenorhabditiselegans by chemical modification of endoplasmic reticulum stress.
Zebrafish Tg(Huc:Kaede) ALS-linked protein disulfide isomerase variants cause motor dysfunction.
Mice RBRC00806 In vivo optical imaging of motor neuron autophagy in a mouse model of amyotrophic lateral sclerosis.
Rats TRM/Kyo(strainID=11) Restoration of aspartoacylase activity in CNS neurons does not ameliorate motor deficits and demyelination in a model of Canavan disease.