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  • 13 Hits
  • 検索条件 : 絞込み (MeSH = Progranulins)
生物種 リソース名 タイトル
実験動物マウス RBRC02370 Reduced progranulin increases tau and α-synuclein inclusions and alters mouse tauopathy phenotypes via glucocerebrosidase.
ヒト・動物細胞 MG6(RCB2403) Progranulin regulates lysosomal function and biogenesis through acidification of lysosomes.
実験動物マウス RBRC02370 Microglia increases the proliferation of retinal precursor cells during postnatal development.
ヒト・動物細胞 ATDC5(RCB0565) The novel adipokine progranulin counteracts IL-1 and TLR4-driven inflammatory response in human and murine chondrocytes via TNFR1.
線虫 tm985 A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells.
線虫 tm985 The Progranulin Cleavage Products, Granulins, Exacerbate TDP-43 Toxicity and Increase TDP-43 Levels.
ヒト・動物細胞 A431(RCB0202) Suppression of copulatory behavior by intracerebroventricular infusion of antisense oligodeoxynucleotide of granulin in neonatal male rats.
実験動物マウス RBRC02370 Progranulin promotes the retinal precursor cell proliferation and the photoreceptor differentiation in the mouse retina.
実験動物マウス , ヒト・動物細胞 RBRC02370 , MC3T3-E1(RCB1126) Progranulin plays crucial roles in preserving bone mass by inhibiting TNF-α-induced osteoclastogenesis and promoting osteoblastic differentiation in mice.
実験動物マウス RBRC02370 Progranulin reduction is associated with increased tau phosphorylation in P301L tau transgenic mice.
実験動物マウス RBRC02370 Progressive retinal degeneration and accumulation of autofluorescent lipopigments in Progranulin deficient mice.
実験動物マウス RBRC02370 Deletion of progranulin exacerbates atherosclerosis in ApoE knockout mice.
線虫 fust-1(tm4439) , pgrn-1(tm985) Reduction of polyglutamine toxicity by TDP-43, FUS and progranulin in Huntington's disease models.