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  • Search Condition : Filter (MeSH = Protein Serine-Threonine Kinases*)
Species Resource Title
Human and Animal Cells MDCK(RCB0995) Down-regulation of Mcl-1 by inhibition of the PI3-K/Akt pathway is required for cell shrinkage-dependent cell death.
Human and Animal Cells L929 Rac is activated by tumor necrosis factor alpha and is involved in activation of Erk.
Human and Animal Cells RBE(RCB1292) , TFK-1(RCB2537) Inhibition of serine/arginine-rich protein kinase-1 (SRPK1) prevents cholangiocarcinoma cells induced angiogenesis.
Human and Animal Cells ATDC5(RCB0565) Involvement of the phosphoinositide 3-kinase/protein kinase B signaling pathway in insulin/IGF-I-induced chondrogenesis of the mouse embryonal carcinoma-derived cell line ATDC5.
Human and Animal Cells SQ-5(RCB0110) Geldanamycin, an inhibitor of Hsp90, sensitizes human tumour cells to radiation.
Human and Animal Cells RAW 264(RCB0535) C2-ceramide inhibits LPS-induced nitric oxide production in RAW 264.7 macrophage cells through down-regulating the activation of Akt.
Human and Animal Cells ST2(RCB0224) Phosphatidylinositol 3-kinase coordinately activates the MEK/ERK and AKT/NFkappaB pathways to maintain osteoclast survival.
Human and Animal Cells ARLJ301-3(RCB0447) Cell adhesion aside from integrin system can abrogate anoikis in rat liver cells by down-regulation of FasL expression, not by activation of PI-3K/Akt and ERK signaling pathway.
Human and Animal Cells 32D(RCB1145) Selective apoptosis of tandemly duplicated FLT3-transformed leukemia cells by Hsp90 inhibitors.
Human and Animal Cells COS-7(RCB0539) , HeLa(RCB0007) Myosin II regulatory light chain as a novel substrate for AIM-1, an aurora/Ipl1p-related kinase from rat.
Cellular slime molds S00335 Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium.
Cellular slime molds S00342 RasC is required for optimal activation of adenylyl cyclase and Akt/PKB during aggregation.
Cellular slime molds S00007 Role of phosphatidylinositol 3' kinase and a downstream pleckstrin homology domain-containing protein in controlling chemotaxis in dictyostelium.
Yeast FY16530(MS203-2) , FY16531(MS202-11) , FY16532(MS111m13) , FY16533(MS105-22C) , FY16534(MS133-1) , FY16535(MS114-3) , FY16536(MS128-15) , FY16537(MS163-10) , FY16538(MS111-6) , FY16539(MS105-25C) etc. The meiotic recombination checkpoint is regulated by checkpoint rad+ genes in fission yeast.
DNA material AxCALacZ (RDB1745) MAPK-upstream protein kinase (MUK) regulates the radial migration of immature neurons in telencephalon of mouse embryo.
Human and Animal Cells MC3T3-E1(RCB1126) Statins inhibit osteoblast migration by inhibiting Rac-Akt signaling.
Human and Animal Cells A549(RCB0098) K-ras gene mutation enhances motility of immortalized airway cells and lung adenocarcinoma cells via Akt activation: possible contribution to non-invasive expansion of lung adenocarcinoma.
Human and Animal Cells MKN45(RCB1001) Inhibition of the PI3K-Akt signaling pathway enhances the sensitivity of Fas-mediated apoptosis in human gastric carcinoma cell line, MKN-45.
Human and Animal Cells KP4(RCB1005) Role of the phosphatidylinositol 3'-kinase-Akt signal pathway in the proliferation of human pancreatic ductal carcinoma cell lines.
Human and Animal Cells MDA-MB-453(RCB1192) alpha-Tocopheryloxybutyric acid enhances necrotic cell death in breast cancer cells treated with chemotherapy agent.