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  • 検索条件 : 絞込み (MeSH = Protein-Tyrosine Kinases / physiology*)
生物種 リソース名 タイトル
ヒト・動物細胞 HeLa(RCB0007) DYRK2 priming phosphorylation of c-Jun and c-Myc modulates cell cycle progression in human cancer cells.
ヒト・動物細胞 DT40(RCB1464) Hypermorphic mutation of phospholipase C, γ2 acquired in ibrutinib-resistant CLL confers BTK independency upon B-cell receptor activation.
ヒト・動物細胞 HeLa.S3(RCB0191) The role of PKN in the regulation of alphaB-crystallin expression via heat shock transcription factor 1.
線虫 tm2526 , tm2663 An EHBP-1-SID-3-DYN-1 axis promotes membranous tubule fission during endocytic recycling.
線虫 tm3084 A Receptor Tyrosine Kinase Plays Separate Roles in Sensory Integration and Associative Learning in C. elegans.
ヒト・動物細胞 ATDC5(RCB0565) Secreted tyrosine kinase Vlk negatively regulates Hedgehog signaling by inducing lysosomal degradation of Smoothened.
ショウジョウバエ breathless, a Drosophila FGF receptor homolog, is essential for migration of tracheal and specific midline glial cells.
線虫 tm2411 , tm3028 , tm501 Behavioral choice between conflicting alternatives is regulated by a receptor guanylyl cyclase, GCY-28, and a receptor tyrosine kinase, SCD-2, in AIA interneurons of Caenorhabditis elegans.
ヒト・動物細胞 Bruton's tyrosine kinase mediates NF-kappa B activation and B cell survival by B cell-activating factor receptor of the TNF-R family.
ヒト・動物細胞 Btk^(-) DT40(RCB1468) , PLC-γ2^(-) DT40(RCB1469) Bruton's tyrosine kinase targets NF-kappaB to the bcl-x promoter via a mechanism involving phospholipase C-gamma2 following B cell antigen receptor engagement.
ヒト・動物細胞 Btk^(-) DT40(RCB1468) Bruton's tyrosine kinase is essential for hydrogen peroxide-induced calcium signaling.
ショウジョウバエ DGRC#102398 Btk-dependent epithelial cell rearrangements contribute to the invagination of nearby tubular structures in the posterior spiracles of Drosophila.
ショウジョウバエ DGRC#109037 The Drosophila Bruton's tyrosine kinase (Btk) homolog is required for adult survival and male genital formation.
ヒト・動物細胞 RAW 264(RCB0535) Cbp recruitment of Csk into lipid rafts is critical to c-Src kinase activity and bone resorption in osteoclasts.
ヒト・動物細胞 MC3T3-E1(RCB1126) Spleen tyrosine kinase suppresses osteoblastic differentiation through MAPK and PKCα.
遺伝子材料 pCAhMCSF Human M-CSF (RDB01524) Physical and functional association of c-Src and adhesion and degranulation promoting adaptor protein (ADAP) in osteoclastogenesis in vitro.
ショウジョウバエ Functional replacement of Drosophila Btk29A with human Btk in male genital development and survival.
ヒト・動物細胞 A549(RCB0098) Activation of ceramidase and ceramide kinase by vanadate via a tyrosine kinase-mediated pathway.
線虫 tm501 C. elegans anaplastic lymphoma kinase ortholog SCD-2 controls dauer formation by modulating TGF-beta signaling.
線虫 tm1664 The C. elegans anaphase promoting complex and MBK-2/DYRK kinase act redundantly with CUL-3/MEL-26 ubiquitin ligase to degrade MEI-1 microtubule-severing activity after meiosis.