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  • Search Condition : Filter (MeSH = Proto-Oncogene Proteins c-met / metabolism)
Species Resource Title
Human and Animal Cells KP4(RCB1005) LY2801653 is an orally bioavailable multi-kinase inhibitor with potent activity against MET, MST1R, and other oncoproteins, and displays anti-tumor activities in mouse xenograft models.
Human and Animal Cells Hep G2(RCB1648) Hepatocyte Growth Factor Enhances Antineoplastic Effect of 5-Fluorouracil by Increasing UPP1 Expression in HepG2 Cells.
Human and Animal Cells U251(RCB0461) , KG-1-C(RCB0270) Reduced expression of hepatocyte growth factor activator inhibitor type-2/placental bikunin (HAI-2/PB) in human glioblastomas: implication for anti-invasive role of HAI-2/PB in glioblastoma cells.
Human and Animal Cells MKN45(RCB1001) Combined drug action of 2-phenylimidazo[2,1-b]benzothiazole derivatives on cancer cells according to their oncogenic molecular signatures.
Human and Animal Cells A549(RCB0098) , LC-2/ad(RCB0440) Inhibition of ABCB1 Overcomes Cancer Stem Cell-like Properties and Acquired Resistance to MET Inhibitors in Non-Small Cell Lung Cancer.
Human and Animal Cells PANC-1(RCB2095) MK2461, a Multitargeted Kinase Inhibitor, Suppresses the Progression of Pancreatic Cancer by Disrupting the Interaction Between Pancreatic Cancer Cells and Stellate Cells.
Human and Animal Cells ST2(RCB0224) , MC3T3-E1(RCB1126) The HGF/Met/NF-κB Pathway Regulates RANKL Expression in Osteoblasts and Bone Marrow Stromal Cells.
Human and Animal Cells Li-7(RCB1941) TBX3 functions as a tumor suppressor downstream of activated CTNNB1 mutants during hepatocarcinogenesis.
Human and Animal Cells B16 melanoma(RCB1283) Glycometabolic Regulation of the Biogenesis of Small Extracellular Vesicles.
Human and Animal Cells MKN45(RCB1001) In Vitro and In Vivo Activity of AMG 337, a Potent and Selective MET Kinase Inhibitor, in MET-Dependent Cancer Models.
Human and Animal Cells RGM1(RCB0876) Epidermal growth factor receptor mediates stress-induced expression of its ligands in rat gastric epithelial cells.
Human and Animal Cells HS-SY-II(RCB2231) Therapeutic potential of TAS-115 via c-MET and PDGFRα signal inhibition for synovial sarcoma.
Human and Animal Cells GCIY(RCB0555) , ECC12(RCB1009) , KE-97(RCB1435) Saracatinib impairs the peritoneal dissemination of diffuse-type gastric carcinoma cells resistant to Met and fibroblast growth factor receptor inhibitors.
Human and Animal Cells MRC-5 Ability of the Met kinase inhibitor crizotinib and new generation EGFR inhibitors to overcome resistance to EGFR inhibitors.
Human and Animal Cells KP4(RCB1005) Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent.
Human and Animal Cells Indazoles as potential c-Met inhibitors: design, synthesis and molecular docking studies.
Human and Animal Cells MKN1(RCB1003) , LMSU(RCB1062) Association of amphiregulin with the cetuximab sensitivity of gastric cancer cell lines.
Human and Animal Cells MRC-5 Paracrine receptor activation by microenvironment triggers bypass survival signals and ALK inhibitor resistance in EML4-ALK lung cancer cells.
Human and Animal Cells MRC-5 Hepatocyte growth factor induces resistance to anti-epidermal growth factor receptor antibody in lung cancer.
Human and Animal Cells A preclinical algorithm of soluble surrogate biomarkers that correlate with therapeutic inhibition of the MET oncogene in gastric tumors.