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  • Search Condition : Filter (MeSH = Pyridazines / pharmacology*)
Species Resource Title
Human and Animal Cells RAW 264(RCB0535) Anti-Inflammatory Profile of Levosimendan in Cecal Ligation-Induced Septic Mice and in Lipopolysaccharide-Stimulated Macrophages.
Human and Animal Cells Lu99(RCB1900) Discovery of imidazo[1,2-b]pyridazine derivatives: selective and orally available Mps1 (TTK) kinase inhibitors exhibiting remarkable antiproliferative activity.
Human and Animal Cells KP4(RCB1005) , EBC-1(RCB1965) Pharmacologic Inhibitor of DNA-PK, M3814, Potentiates Radiotherapy and Regresses Human Tumors in Mouse Models.
Human and Animal Cells KP4(RCB1005) Translational pharmacokinetic-pharmacodynamic modeling of preclinical and clinical data of the oral MET inhibitor tepotinib to determine the recommended phase II dose.
Human and Animal Cells 32Dcl3 Functional characterization, localization, and inhibitor sensitivity of the TPR-FGFR1 fusion in 8p11 myeloproliferative syndrome.
Human and Animal Cells Ba/F3(RCB0805) Targeting wild-type and mutationally activated FGFR4 in rhabdomyosarcoma with the inhibitor ponatinib (AP24534).
Human and Animal Cells JHUEM-2(RCB1551) The N550K/H mutations in FGFR2 confer differential resistance to PD173074, dovitinib, and ponatinib ATP-competitive inhibitors.
Human and Animal Cells LoVo(RCB1639) , HCT116(RCB2979) EMD 1214063 and EMD 1204831 constitute a new class of potent and highly selective c-Met inhibitors.