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  • Search Condition : Filter (MeSH = Signal Transduction / drug effects*)
Species Resource Title
Human and Animal Cells A431(RCB0202) Lysophosphatidic acid inhibits epidermal-growth-factor-induced Stat1 signaling in human epidermoid carcinoma A431 cells.
C.elegans tm1011 Trigonelline Extends the Lifespan of C. Elegans and Delays the Progression of Age-Related Diseases by Activating AMPK, DAF-16, and HSF-1.
C.elegans tm1978 Orientin Prolongs the Longevity of Caenorhabditis elegans and Postpones the Development of Neurodegenerative Diseases via Nutrition Sensing and Cellular Protective Pathways.
Human and Animal Cells CHO-K1(RCB0285) Lysophosphatidylcholine transduces Ca2+ signaling via the platelet-activating factor receptor in macrophages.
Human and Animal Cells HS-Sch-2(RCB2230) , HS-PSS(RCB2362) , YST-1(RCB2136) Prognostic significance of AKT/mTOR and MAPK pathways and antitumor effect of mTOR inhibitor in NF1-related and sporadic malignant peripheral nerve sheath tumors.
Human and Animal Cells ATDC5(RCB0565) Expression and Role of IL-1β Signaling in Chondrocytes Associated with Retinoid Signaling during Fracture Healing.
Human and Animal Cells RAW 264(RCB0535) Anti-Inflammatory Effects of Heliangin from Jerusalem Artichoke (Helianthus tuberosus) Leaves Might Prevent Atherosclerosis.
Human and Animal Cells MC3T3-E1(RCB1126) Tctex-1 augments G protein-coupled receptor-mediated Gs signaling by activating adenylyl cyclase.
Human and Animal Cells PC-12(RCB0009) Inhibition of the RhoA/Rho kinase system attenuates catecholamine biosynthesis in PC 12 rat pheochromocytoma cells.
Human and Animal Cells KGN(RCB1154) Salidroside alleviates oxidative stress and apoptosis via AMPK/Nrf2 pathway in DHT-induced human granulosa cell line KGN.
Human and Animal Cells 10T1/2(RCB0247) , PANC-1(RCB2095) New hedgehog/GLI-signaling inhibitors from Adenium obesum.
Human and Animal Cells 8505C(RCB2103) , HTC/C3(RCB0452) , HOTHC(RCB0662) BRAF Inhibitors Induce Feedback Activation of RAS Pathway in Thyroid Cancer Cells.
Human and Animal Cells MG6(RCB2403) Geranylgeraniol Inhibits Lipopolysaccharide-Induced Inflammation in Mouse-Derived MG6 Microglial Cells via NF-κB Signaling Modulation.
Human and Animal Cells ST2(RCB0224) Mechanisms involved in suppression of osteoclast supportive activity by transforming growth factor-β1 via the ubiquitin-proteasome system.
Human and Animal Cells PC-12(RCB0009) Oleic acid stimulates glucose uptake into adipocytes by enhancing insulin receptor signaling.
DNA material pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) Macrothrombocytopenia of Takenouchi-Kosaki syndrome is ameliorated by CDC42 specific- and lipidation inhibitors in MEG-01 cells.
Human and Animal Cells PANC-1(RCB2095) Inhibitory activity of flavonoids from Ephedrae Herba on hypoxia signaling in PANC-1 cells and the evaluation of their mechanisms.
Human and Animal Cells PK-1(RCB1972) , KLM-1(RCB2138) Avarol induces apoptosis in pancreatic ductal adenocarcinoma cells by activating PERK-eIF2α-CHOP signaling.
DNA material pENTR4-H1 (RDB04395) Regulation of alkaline ceramidase activity by the c-Src-mediated pathway.
Human and Animal Cells HuH-7 First Selective Small Molecule Inhibitor of FGFR4 for the Treatment of Hepatocellular Carcinomas with an Activated FGFR4 Signaling Pathway.