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  • Search Condition : Filter (MeSH = Simvastatin / pharmacology*)
Species Resource Title
Human and Animal Cells WEHI-3(RCB0035) , Ba/F3(RCB0805) Synergistic killing effect of imatinib and simvastatin on imatinib-resistant chronic myelogenous leukemia cells.
Human and Animal Cells Hep G2(RCB1886) A prospective mechanism and source of cholesterol uptake by Plasmodium falciparum-infected erythrocytes co-cultured with HepG2 cells.
Human and Animal Cells RAW 264(RCB0535) Stimulation of osteoclast formation by RANKL requires interferon regulatory factor-4 and is inhibited by simvastatin in a mouse model of bone loss.
Human and Animal Cells ST2(RCB0224) , 10T1/2(RCB0247) Involvement of geranylgeranylation of Rho and Rac GTPases in adipogenic and RANKL expression, which was inhibited by simvastatin.
Human and Animal Cells MMAc(RCB0808) , G-361(RCB0991) Simvastatin inhibits growth via apoptosis and the induction of cell cycle arrest in human melanoma cells.
Human and Animal Cells HL-60-R2(RCB1550) The possibility of simvastatin as a chemotherapeutic agent for all-trans retinoic acid-resistant promyelocytic leukemia.
Human and Animal Cells ST2(RCB0224) Statins augment vascular endothelial growth factor expression in osteoblastic cells via inhibition of protein prenylation.
Human and Animal Cells Jurkat(RCB0806) , J774 HMG-CoA reductase inhibitors enhance phagocytosis by upregulating ATP-binding cassette transporter A7.
Human and Animal Cells MLC-6(RCB1536) Simvastatin inhibits osteoclast differentiation induced by bone morphogenetic protein-2 and RANKL through regulating MAPK, AKT and Src signaling.
Human and Animal Cells C2C12(RCB0987) Simvastatin suppresses the differentiation of C2C12 myoblast cells via a Rac pathway.
Mice RBRC01390 Simvastatin lowers reactive oxygen species level by Nrf2 activation via PI3K/Akt pathway.