生物種
|
リソース名
|
RRC ID
|
タイトル
|
ジャーナル
|
公開日
|
外部リンク
|
線虫
|
tm985
|
75949
|
Chemical and genetic rescue of in vivo progranulin-deficient lysosomal and autophagic defects.
|
Proc Natl Acad Sci U S A |
2021-6-22 |
Pubmed
Full text
|
ヒト・動物細胞
|
MIA Paca2(RCB2094)
,
LU65(RCB1967)
|
71616
|
Characterisation of a novel KRAS G12C inhibitor ASP2453 that shows potent anti-tumour activity in KRAS G12C-mutated preclinical models.
|
Br J Cancer |
2022-3-1 |
Pubmed
Full text
|
ヒト・動物細胞
|
HeLa(RCB0007)
|
69796
|
Small molecule targeting r(UGGAA)n disrupts RNA foci and alleviates disease phenotype in Drosophila model.
|
Nat Commun |
2021-1-11 |
Pubmed
Full text
|
ヒト・動物細胞
|
EBC-1(RCB1965)
|
69767
|
PARP7 negatively regulates the type I interferon response in cancer cells and its inhibition triggers antitumor immunity.
|
Cancer Cell |
2021-9-13 |
Pubmed
Full text
|
ヒト・動物細胞
|
A549
,
MKN74(RCB1002)
,
PANC-1(RCB2095)
,
MIA Paca2(RCB2094)
|
69631
|
Identification of a Small Molecule That Enhances Ferroptosis via Inhibition of Ferroptosis Suppressor Protein 1 (FSP1).
|
ACS Chem Biol |
2022-2-18 |
Pubmed
Full text
|
ヒト・動物細胞
|
OS-RC-2(RCB0735)
,
TUHR10TKB(RCB1275)
,
TUHR14TKB(RCB1383)
|
63501
|
Oncogenic roles of TOPK and MELK, and effective growth suppression by small molecular inhibitors in kidney cancer cells.
|
Oncotarget |
2016-4-5 |
Pubmed
Full text
|
線虫
|
tm611
|
59411
|
Proteinase K is an activator for the male-dependent spermiogenesis pathway in Caenorhabditis elegans: Its application to pharmacological dissection of spermiogenesis.
|
Genes Cells |
2019-3-1 |
Pubmed
Full text
|
ヒト・動物細胞
|
TE-4(RCB2097)
|
54001
|
Small molecule inhibitors and CRISPR/Cas9 mutagenesis demonstrate that SMYD2 and SMYD3 activity are dispensable for autonomous cancer cell proliferation.
|
PLoS One |
2018-6-1 |
Pubmed
Full text
|
線虫
|
tm1325
|
53277
|
Chemical activation of a food deprivation signal extends lifespan.
|
Aging Cell |
2016-10-1 |
Pubmed
Full text
|
ヒト・動物細胞
|
HCT116(RCB2979)
|
52611
|
H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers.
|
Nat Med |
2018-5-1 |
Pubmed
Full text
|
線虫
|
tm1689
|
51509
|
Rescue of ATXN3 neuronal toxicity in Caenorhabditiselegans by chemical modification of endoplasmic reticulum stress.
|
Dis Model Mech |
2017-12-19 |
Pubmed
Full text
|
線虫
|
tm4067
|
46425
|
Stimulation of host immune defenses by a small molecule protects C. elegans from bacterial infection.
|
PLoS Genet |
2012-1-1 |
Pubmed
Full text
|
シロイヌナズナ / 植物培養細胞・遺伝子
|
rpc00008
|
36997
|
Novel Abscisic Acid Antagonists Identified with Chemical Array Screening.
|
Chembiochem |
2015-11-1 |
Pubmed
Full text
|
遺伝子材料
|
pCAG-HIVgp (RDB04394)
,
pCMV-VSV-G (RDB04392).
|
35571
|
Rapid, efficient, and simple motor neuron differentiation from human pluripotent stem cells.
|
Mol Brain |
2015-12-1 |
Pubmed
Full text
|