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  • Search Condition : Filter (MeSH = Spiro Compounds / pharmacology)
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Human and Animal Cells PLC-γ2^(-) DT40(RCB1469) , Btk^(-) DT40(RCB1468) , Syk^(-) DT40(RCB1470) B cell receptor-induced cAMP-response element-binding protein activation in B lymphocytes requires novel protein kinase Cdelta.
Prokaryotes B. subtilis Armeniaspirols inhibit the AAA+ proteases ClpXP and ClpYQ leading to cell division arrest in Gram-positive bacteria.
Human and Animal Cells K562(RCB0027) Effect of a novel antibiotic, heliquinomycin, on DNA helicase and cell growth.
Human and Animal Cells StromaNKtert(RCB2350) Bone marrow stroma-secreted cytokines protect JAK2(V617F)-mutated cells from the effects of a JAK2 inhibitor.
Human and Animal Cells HeLa.S3(RCB1525) Splicing modulators elicit global translational repression by condensate-prone proteins translated from introns.
Human and Animal Cells KLM-1(RCB2138) , PK-45H(RCB1973) , PK-59(RCB1901) , KP4(RCB1005) , PK-8(RCB2700) Human pancreatic cancer cells under nutrient deprivation are vulnerable to redox system inhibition.
DNA material , Human and Animal Cells CS-CA-MCS (RDB05963) , 10T1/2(RCB0247) Cigarette smoke extract induces ferroptosis in vascular smooth muscle cells.
Pathogenic eukaryotic microorganisms 病原原虫：Ld003 Oral activity of the antimalarial endoperoxide 6-(1,2,6,7-tetraoxaspiro[7.11]nonadec-4-yl)hexan-1-ol (N-251) against Leishmania donovani complex.
Human and Animal Cells Dietary ginger constituents, galanals A and B, are potent apoptosis inducers in Human T lymphoma Jurkat cells.
Rats Enhanced reactivity to vasopressin in rat basilar arteries during vasospasm after subarachnoid hemorrhage.