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Human and Animal Cells PC-12(RCB0009) , SK-N-SH(RCB0426) Sunitinib inhibits catecholamine synthesis and secretion in pheochromocytoma tumor cells by blocking VEGF receptor 2 via PLC-γ-related pathways.
Human and Animal Cells HuH-6(RCB1367) The Collagen Gel Droplet-embedded Culture Drug Sensitivity Test in Relapsed Hepatoblastoma.
Human and Animal Cells LC-2/ad(RCB0440) EGF Induced RET Inhibitor Resistance in CCDC6-RET Lung Cancer Cells.
Human and Animal Cells PC-12(RCB0009) Inhibition of autophagy enhances sunitinib-induced cytotoxicity in rat pheochromocytoma PC12 cells.
Human and Animal Cells IL6-STAT3-HIF signaling and therapeutic response to the angiogenesis inhibitor sunitinib in ovarian clear cell cancer.
Drosophila 8222R-3 Platelet-derived growth factor/vascular endothelial growth factor receptor inactivation by sunitinib results in Tsc1/Tsc2-dependent inhibition of TORC1.
Human and Animal Cells PC-12(RCB0009) , SK-N-SH(RCB0426) Sunitinib induces apoptosis in pheochromocytoma tumor cells by inhibiting VEGFR2/Akt/mTOR/S6K1 pathways through modulation of Bcl-2 and BAD.