生物種
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リソース名
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RRC ID
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タイトル
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ジャーナル
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公開日
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外部リンク
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遺伝子材料
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p3xFLAG-CMV10-hTel2 (RDB19795)
,
p3xFLAG-CMV10-hTti1 (RDB19800)
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73637
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Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly.
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J Biol Chem |
2010-6-25 |
Pubmed
Full text
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遺伝子材料
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pMXs-IP-EGFP-hATG13 (RDB19625)
,
pME18s-HA-hFIP200 (RDB19769)
,
pEGFP-C1-hAtg13 (RDB19770)
,
p3xFLAG-CMV10-hAtg13 (RDB19771)
,
p3xFLAG-CMV14-mULK1 (RDB19772)
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72405
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Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy.
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Mol Biol Cell |
2009-4-1 |
Pubmed
Full text
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遺伝子材料
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pMXs-IP-EGFP-hFIP200 (RDB19623)
,
pMXs-IP-EGFP-mAtg5 (RDB19634)
,
p3xFLAG-CMV10-hFIP200 (RDB19762)
,
pMXs-IP-EGFP-ULK1(K46N) (RDB19780)
,
pMXs-IP-EGFP-LC3 (RDB19798)
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72403
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FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells.
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J Cell Biol |
2008-5-5 |
Pubmed
Full text
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ヒト・動物細胞
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A549(RCB0098)
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70500
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The oncogene-dependent resistance to reprogramming unveils cancer therapeutic targets.
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Cell Rep |
2022-4-26 |
Pubmed
Full text
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ヒト・動物細胞
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PC-3(RCB2145)
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70457
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Asteltoxin inhibits extracellular vesicle production through AMPK/mTOR-mediated activation of lysosome function.
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Sci Rep |
2022-4-23 |
Pubmed
Full text
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ヒト・動物細胞
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ST2(RCB0224)
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64734
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Peptide drugs accelerate BMP-2-induced calvarial bone regeneration and stimulate osteoblast differentiation through mTORC1 signaling.
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Bioessays |
2016-8-1 |
Pubmed
Full text
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ヒト・動物細胞
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CACO-2(RCB0988)
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COLO205(RCB2127)
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52423
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Rebamipide suppresses 5-fluorouracil-induced cell death via the activation of Akt/mTOR pathway and regulates the expression of Bcl-2 family proteins.
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Toxicol In Vitro |
2018-2-1 |
Pubmed
Full text
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ヒト・動物細胞
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PC-12(RCB0009)
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44212
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Inhibition of autophagy enhances sunitinib-induced cytotoxicity in rat pheochromocytoma PC12 cells.
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J Pharmacol Sci |
2013-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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ATDC5(RCB0565)
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43267
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mTOR signaling contributes to chondrocyte differentiation.
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Dev Dyn |
2008-3-1 |
Pubmed
Full text
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ヒト・動物細胞
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MC3T3-E1(RCB1126)
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43017
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Ultrasound induces hypoxia-inducible factor-1 activation and inducible nitric-oxide synthase expression through the integrin/integrin-linked kinase/Akt/mammalian target of rapamycin pathway in osteoblasts.
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J Biol Chem |
2007-8-31 |
Pubmed
Full text
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ヒト・動物細胞
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42826
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Amino acid limitation induces expression of ATF5 mRNA at the post-transcriptional level.
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Life Sci |
2007-2-6 |
Pubmed
Full text
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ヒト・動物細胞
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B16 melanoma
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42369
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Negative regulation of melanogenesis by phospholipase D1 through mTOR/p70 S6 kinase 1 signaling in mouse B16 melanoma cells.
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J Cell Physiol |
2005-12-1 |
Pubmed
Full text
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ヒト・動物細胞
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39338
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Cyclin D1 expression mediated by phosphatidylinositol 3-kinase through mTOR-p70(S6K)-independent signaling in growth factor-stimulated NIH 3T3 fibroblasts.
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Mol Cell Biol |
1999-2-1 |
Pubmed
Full text
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ヒト・動物細胞
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38229
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Inhibition of MEK/ERK signaling induces apoptosis of acute myelogenous leukemia cells via inhibition of eukaryotic initiation factor 4E-binding protein 1 and down-regulation of Mcl-1.
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Apoptosis |
2010-7-1 |
Pubmed
Full text
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ヒト・動物細胞
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37729
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Leucine restriction inhibits chondrocyte proliferation and differentiation through mechanisms both dependent and independent of mTOR signaling.
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Am J Physiol Endocrinol Metab |
2009-6-1 |
Pubmed
Full text
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ショウジョウバエ
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6975R-2
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6975R-8
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21960
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AKT and TOR signaling set the pace of the circadian pacemaker.
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Curr Biol |
2010-7-13 |
Pubmed
Full text
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ショウジョウバエ
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16908R-1
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21958
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Modularity and hormone sensitivity of the Drosophila melanogaster insulin receptor/target of rapamycin interaction proteome.
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Mol Syst Biol |
2011-11-8 |
Pubmed
Full text
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ショウジョウバエ
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21846
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Multifaceted roles of PTEN and TSC orchestrate growth and differentiation of Drosophila blood progenitors.
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Development |
2012-10-1 |
Pubmed
Full text
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ヒト・動物細胞
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ST2(RCB0224)
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19331
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Down-regulation of mTOR leads to up-regulation of osteoprotegerin in bone marrow cells.
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Biochem Biophys Res Commun |
2009-6-19 |
Pubmed
Full text
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ショウジョウバエ
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5092R-2
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4320R-2
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10539R-3
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15551
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MAP4K3 is a component of the TORC1 signalling complex that modulates cell growth and viability in Drosophila melanogaster.
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PLoS One |
2011-1-18 |
Pubmed
Full text
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