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  • 検索条件 : 絞込み (MeSH = TOR Serine-Threonine Kinases / antagonists & inhibitors)
生物種 リソース名 タイトル
ヒト・動物細胞 PANC-1(RCB2095) Structure-activity relationship and mechanistic study on guggulsterone derivatives; Discovery of new anti-pancreatic cancer candidate.
ヒト・動物細胞 HuH-7(RCB1366) Targeting cap-dependent translation to inhibit Chikungunya virus replication: selectivity of p38 MAPK inhibitors to virus-infected cells due to autophagy-mediated down regulation of phospho-ERK.
ヒト・動物細胞 JHOM-1(RCB1676) , JHOM-2B(RCB1682) , OMC-3(RCB0755) Synergistic antitumor effects of combination PI3K/mTOR and MEK inhibition (SAR245409 and pimasertib) in mucinous ovarian carcinoma cells by fluorescence resonance energy transfer imaging.
ヒト・動物細胞 Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) , Atg7 +/+ MEFs(RCB3706) , Atg7 -/- MEFs(RCB3707) Glutamine-dependent lysosome homeostatic changes induced by starvation and lysosome inhibition.
ヒト・動物細胞 TGBC2TKB(RCB1130) Histone Deacetylase Inhibitors Inhibit the Proliferation of Gallbladder Carcinoma Cells by Suppressing AKT/mTOR Signaling.
ヒト・動物細胞 HL60(RCB0041) , U-937 DE-4(RCB0435) Nitrogen-containing bisphosphonates induce apoptosis of hematopoietic tumor cells via inhibition of Ras signaling pathways and Bim-mediated activation of the intrinsic apoptotic pathway.
ヒト・動物細胞 A172(RCB2530) Crosstalk between the PI3K/mTOR and MEK/ERK pathways involved in the maintenance of self-renewal and tumorigenicity of glioblastoma stem-like cells.
線虫 tm776 , tm1146 The genetics of isoflurane-induced developmental neurotoxicity.
ヒト・動物細胞 MC3T3-E1(RCB1126) PDMP, a ceramide analogue, acts as an inhibitor of mTORC1 by inducing its translocation from lysosome to endoplasmic reticulum.
ヒト・動物細胞 Hep G2 Diversity of amino acid signaling pathways on autophagy regulation: a novel pathway for arginine.
ヒト・動物細胞 PANC-1(RCB2095) (+)-Grandifloracin, an antiausterity agent, induces autophagic PANC-1 pancreatic cancer cell death.
ヒト・動物細胞 Akt inactivation induces endoplasmic reticulum stress-independent autophagy in fibroblasts from patients with Pompe disease.
ヒト・動物細胞 NUGC-4(RCB1939) , MKN7(RCB0999) , Kato III(RCB2088) , MKN45(RCB1001) , MKN1(RCB1003) , MKN74(RCB1002) Inhibition of the mTOR/S6K signal is necessary to enhance fluorouracil-induced apoptosis in gastric cancer cells with HER2 amplification.
ラット F344-Depdc5em1kyo , F344-Depdc5em2kyo Depdc5 knockout rat: A novel model of mTORopathy.
ヒト・動物細胞 MS-1(RCB0725) , Lu-139(RCB0469) Control of the MYC-eIF4E axis plus mTOR inhibitor treatment in small cell lung cancer.
遺伝子材料 CSII-EF-RfA (RDB04387) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394). Activation of mTOR by human T-cell leukemia virus type 1 Tax is important for the transformation of mouse T cells to interleukin-2-independent growth.
実験動物マウス RBRC02231 Autophagy and mTORC1 regulate the stochastic phase of somatic cell reprogramming.
ショウジョウバエ 8222R-3 Platelet-derived growth factor/vascular endothelial growth factor receptor inactivation by sunitinib results in Tsc1/Tsc2-dependent inhibition of TORC1.
ショウジョウバエ Select interneuron clusters determine female sexual receptivity in Drosophila.
ヒト・動物細胞 A172(RCB2530) FoxO3a functions as a key integrator of cellular signals that control glioblastoma stem-like cell differentiation and tumorigenicity.