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生物種 リソース名 タイトル
研究用ヒト臍帯血幹細胞 E2F-6 suppresses growth-associated apoptosis of human hematopoietic progenitor cells by counteracting proapoptotic activity of E2F-1.
遺伝子材料 pcDNA3.1(+)-SIX1 (RDB15335) SIX1 maintains tumor basal cells via transforming growth factor-β pathway and associates with poor prognosis in esophageal cancer.
遺伝子材料 , ヒト・動物細胞 Genome Network Project Human cDNA IRCB003O22 (HGY121558) , MKN74(RCB1002) , MKN45(RCB1001) CCAAT/enhancer-binding protein α decreases the viability of gastric cancer cells.
遺伝子材料 pcDNA3.1-His-hGLI1 (RDB08063) , pcDNA3.1-His-Gli2 (RDB08065) , CSII-CMV-MCS-IRES2-Bsd (RDB04385) GLI-mediated Keratin 17 expression promotes tumor cell growth through the anti-apoptotic function in oral squamous cell carcinomas.
遺伝子材料 pEF-mouse T7-Munc13-4 (RDB15181) Functional characterization of two RAB27A missense mutations found in Griscelli syndrome type 2.
遺伝子材料 CSII-CMV-RfA (RDB04386) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394). Oncogenic transformation of human ovarian surface epithelial cells with defined cellular oncogenes.
遺伝子材料 pENTR4-H1 (RDB04395) Fibroblast-led cancer cell invasion is activated by epithelial-mesenchymal transition through platelet-derived growth factor BB secretion of lung adenocarcinoma.
遺伝子材料 pTcf7wtluc (RDB02968) , pTcf7mtluc (RDB02969). APC Mutations as a Potential Biomarker for Sensitivity to Tankyrase Inhibitors in Colorectal Cancer.
遺伝子材料 pSV2 proto-ret (RDB01163) Cloning and expression of the ret proto-oncogene encoding a tyrosine kinase with two potential transmembrane domains.
遺伝子材料 pCIneoFLAG-LATS1 (RDB14396) , pCIneoFHF-PP1A (RDB14397) , pCIneoFHF-PP2A (RDB14398) , pCIneoLuc-TAZ (RDB14399) , pCIneoFH-TAZ (RDB14400) , pCIneoEGFPC2 (RDB14401) , pLL3.7-FLAG-YAP1 (RDB14395) Validation of chemical compound library screening for transcriptional co-activator with PDZ-binding motif inhibitors using GFP-fused transcriptional co-activator with PDZ-binding motif.
遺伝子材料 pCMV-Tag2B_ALDH2 (RDB13740) , pLEX_ALDH2WT (RDB13741) , pLEX_ALDH2Glu504Lys (RDB13742) Protective role of ALDH2 against acetaldehyde-derived DNA damage in oesophageal squamous epithelium.
ヒト・動物細胞 ACC-MESO-1(RCB2292) , ACC-MESO-4(RCB2293) HEG1 is a novel mucin-like membrane protein that serves as a diagnostic and therapeutic target for malignant mesothelioma.
遺伝子材料 CSIV-CMV-MCS-IRES2-Venus (RDB08257) Characterization of common marmoset dysgerminoma-like tumor induced by the lentiviral expression of reprogramming factors.
遺伝子材料 pENTR4-H1 (RDB04395) , CS-RfA-EG (RDB04391) , CSII-CMV-RfA-IRES2-Venus (RDB04388) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394). CD200-positive cancer associated fibroblasts augment the sensitivity of Epidermal Growth Factor Receptor mutation-positive lung adenocarcinomas to EGFR Tyrosine kinase inhibitors.
遺伝子材料 MMP11-miR-139-5P wild (RDB14547) , MMP11-miR-139-5P del (RDB14548) , MMP11-miR-139-3P wild (RDB14549) , MMP11-miR-139-3P del (RDB14550). Dual tumor-suppressors miR-139-5p and miR-139-3p targeting matrix metalloprotease 11 in bladder cancer.
ヒト・動物細胞 A549(RCB0098) , PC-3(RCB2145) Frequent silencing of the candidate tumor suppressor TRIM58 by promoter methylation in early-stage lung adenocarcinoma.
ヒト・動物細胞 PK-8(RCB2700) , KLM-1(RCB2138) A new PDAC mouse model originated from iPSCs-converted pancreatic cancer stem cells (CSCcm).
遺伝子材料 CS-CA-GFP (RDB05964) , pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393). Expression of Tim-1 in primary CNS lymphoma.
遺伝子材料 , ヒト・動物細胞 pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393). , CACO-2(RCB0988) miR-663a regulates growth of colon cancer cells, after administration of antimicrobial peptides, by targeting CXCR4-p21 pathway.
遺伝子材料 pGEX-6P-3/GST-TAT-ODD/3-0-Casp3 (RDB14403) , pEF/HRE-Fluc (RDB14404). Hypoxia-inducible factor-targeting prodrug TOP3 combined with gemcitabine or TS-1 improves pancreatic cancer survival in an orthotopic model.