RRC ID 35491
著者 Yoshida H, Maki Y, Furuike S, Sakai A, Ueta M, Wada A.
タイトル YqjD is an inner membrane protein associated with stationary-phase ribosomes in Escherichia coli.
ジャーナル J Bacteriol
Abstract Here, we provide evidence that YqjD, a hypothetical protein of Escherichia coli, is an inner membrane and ribosome binding protein. This protein is expressed during the stationary growth phase, and expression is regulated by stress response sigma factor RpoS. YqjD possesses a transmembrane motif in the C-terminal region and associates with 70S and 100S ribosomes at the N-terminal region. Interestingly, E. coli possesses two paralogous proteins of YqjD, ElaB and YgaM, which are expressed and bind to ribosomes in a similar manner to YqjD. Overexpression of YqjD leads to inhibition of cell growth. It has been suggested that YqjD loses ribosomal activity and localizes ribosomes to the membrane during the stationary phase.
巻・号 194(16)
ページ 4178-83
公開日 2012-8-1
DOI 10.1128/JB.00396-12
PII JB.00396-12
PMID 22661687
PMC PMC3416271
MeSH Bacterial Proteins / metabolism Escherichia coli / chemistry Escherichia coli / growth & development Escherichia coli / metabolism Escherichia coli / physiology* Escherichia coli Proteins / genetics Escherichia coli Proteins / metabolism* Gene Expression Regulation, Bacterial Membrane Proteins / genetics Membrane Proteins / metabolism* Protein Binding Protein Interaction Mapping Ribosomes / chemistry Ribosomes / metabolism* Sigma Factor / metabolism
IF 3.006
引用数 18
WOS 分野 MICROBIOLOGY
リソース情報
原核生物(大腸菌) ME7985(W3110)? JW3069-KC JW5437-KC