RRC ID 50565
著者 Nishimura T, Yamada K, Fujimori C, Kikuchi M, Kawasaki T, Siegfried KR, Sakai N, Tanaka M.
タイトル Germ cells in the teleost fish medaka have an inherent feminizing effect.
ジャーナル PLoS Genet
Abstract AUTHOR SUMMARY:Germ cells are the only cells that can transfer genetic materials to the next generation via the sperm or egg. However, recent analyses in teleosts revealed another essential role of germ cells: feminizing the gonads. In our study, medaka mutants in which gametogenesis was blocked at specific stages provides the novel view that the feminizing effect of germ cells occurs in parallel with other reproductive elements, such as meiosis, the sexual fate decision of germ cells, and gametogenesis. Germ cells in medaka may have a potential to feminize gonads at the moment they have developed.
巻・号 14(3)
ページ e1007259
公開日 2018-3-1
DOI 10.1371/journal.pgen.1007259
PII PGENETICS-D-17-01674
PMID 29596424
PMC PMC5875746
MeSH Animals Cell Lineage Female Feminization* Gametogenesis Germ Cells / cytology* Male Meiosis Oryzias / genetics* Sex Differentiation
IF 5.175
引用数 8
リソース情報
メダカ fosmid clone (GOLWFno462_j06) OK-Cab (MT830)