RRC ID |
15493
|
著者 |
Liedtke D, Erhard I, Schartl M.
|
タイトル |
snail gene expression in the medaka, Oryzias latipes.
|
ジャーナル |
Gene Expr Patterns
|
Abstract |
Snail transcription factors have prominent roles during embryonic development of vertebrates. They are often involved in cell migration processes during neural crest development, epithelial-mesenchymal transition and cancer progression. Comparative expression studies of snai gene family members in different vertebrate species are expected to contribute to a better understanding of their roles during development and reflect their evolutionary history. To investigate and to compare the expression patterns of snai genes in a second main fish model we used the medaka fish (Oryzias latipes), a complementary teleost model to zebrafish. We identified three snai gene family members, snai1a, snai1b and snai2. Phylogenetic and synteny analysis show a close relatedness of all family members to other vertebrate snai genes. Surprisingly, no homologue of snai3 could be identified in medaka, although this gene is present in zebrafish and the puffer fishes. Here we demonstrate that while most expression domains of medaka snai genes are comparable to zebrafish, the contribution of the individual paralogs to the overall pattern differs between the two teleosts and indicate lineage specific expression shuffling.
|
巻・号 |
11(3-4)
|
ページ |
181-9
|
公開日 |
2011-1-1
|
DOI |
10.1016/j.gep.2010.11.003
|
PII |
S1567-133X(10)00118-3
|
PMID |
21094700
|
MeSH |
Animals
Gastrula / metabolism
Gastrulation / physiology
Gene Expression Regulation, Developmental
In Situ Hybridization
Likelihood Functions
Mesoderm / metabolism
Neural Crest / cytology
Neural Crest / metabolism
Oryzias / embryology
Oryzias / genetics*
Phylogeny
Sequence Alignment
Snail Family Transcription Factors
Somites / metabolism
Transcription Factors / genetics
Transcription Factors / metabolism*
Transcription, Genetic
Zebrafish / embryology
Zebrafish / genetics
|
IF |
0.897
|
引用数 |
2
|
WOS 分野
|
DEVELOPMENTAL BIOLOGY
GENETICS & HEREDITY
|
リソース情報 |
メダカ |
database
carbio strain (OK-Cab (MT830))
i3 albino strain(i-3(b) (MT65)) |